Figure 12.62. Adhesion between leukocytes and endothelial cells.

Figure 12.62Adhesion between leukocytes and endothelial cells

Leukocytes leave the circulation at sites of tissue inflammation by interacting with the endothelial cells of capillary walls. The first step in this interaction is the binding of leukocyte selectins to carbohydrate ligands on the endothelial cell surface. This step is followed by more stable interactions between leukocyte integrins and members of the Ig superfamily (ICAMs) on endothelial cells.

From: Cell-Cell Interactions

Cover of The Cell
The Cell: A Molecular Approach. 2nd edition.
Cooper GM.
Sunderland (MA): Sinauer Associates; 2000.
Copyright © 2000, Geoffrey M Cooper.

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