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Sharma P, Boyers D, Boachie C, et al. Elucigene FH20 and LIPOchip for the Diagnosis of Familial Hypercholesterolaemia: A Systematic Review and Economic Evaluation. Southampton (UK): NIHR Journals Library; 2012 Mar. (Health Technology Assessment, No. 16.17.)

Cover of Elucigene FH20 and LIPOchip for the Diagnosis of Familial Hypercholesterolaemia: A Systematic Review and Economic Evaluation

Elucigene FH20 and LIPOchip for the Diagnosis of Familial Hypercholesterolaemia: A Systematic Review and Economic Evaluation.

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Acknowledgements

We thank the study authors we contacted who provided additional details of their studies, the Royal College of Physicians for supplying access to the economic model used to inform previous NICE guidance, the NICE assessment subgroup specialist members for their responses to our queries and Lara Kemp for secretarial support. We would also like to thank Dr Kevin Kelly for providing guidance and advice on the development of the MOLU costing methodology used in this project. Cynthia Fraser supervised the work involved in developing and running the search strategies. Graeme MacLennan provided oversight to the statistical analysis. The Health Services Research Unit and Health Economics Research Unit, Institute of Applied Health Sciences, University of Aberdeen, are both core funded by the Chief Scientist Office of the Scottish Government Health Directorates.

Contribution of authors

Pawana Sharma (Research Fellow) and Graham Mowatt (Senior Research Fellow) screened the search results, assessed full-text studies for inclusion and undertook data extraction and quality assessment. Pawana Sharma drafted the chapter reporting the results of the diagnostic accuracy studies. Dwayne Boyers (Research Fellow) undertook the economic modelling and drafted the chapter on cost-effectiveness, along with Mary Kilonzo (Research Fellow) and Paul McNamee (Reader in Health Economics). Zosia Miedzybrodzka (Reader in Medical Genetics) and William Simpson (Consultant Chemical Pathologist) drafted the background chapter and provided expert advice on clinical aspects of the review. Charles Boachie (Statistician) conducted the statistical analysis. Fiona Stewart (Information Specialist) developed and ran the search strategies, obtained papers and formatted the references. All authors assisted in preparing the manuscript and commenting on drafts.

© 2012, Crown Copyright.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK97927

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