Table 56Dietary supplements (Vitamin D and calcium)

Event GroupCalciumVitamin D
Number of TrialsOR (95% CI)Number of TrialsOR (95% CI)
Cardiovascular
Acute Coronary Syndrome0NR0NR
 Cardiac Death0NR0NR
Myocardial infarction51.31 (1.02, 1.67)*0NR
 Cerebrovascular Events (serious)11.56 (1.05, 2.33)*0NR
 Pulmonary Embolism0NR0NR
 Thromboembolic Events0NR0NR
Cancer
Cancer0NR0NR
 Breast Cancer0NR0NR
 Colon Cancer0NR0NR
 Lung Cancer0NR0NR
 Osteosarcoma0NR0NR
GI
GI (mild)10.79 (0.33, 1.87)10.27 (0.04, 1.11)
 Upper GI (excluding esophagus)10.79 (0.33, 1.87)20.27 (0.04, 1.11)
 Reflux and Esophageal0NR0NR
GI (serious)0NR0NR
 Esophageal (serious)0NR0NR
 Upper GI Perforations, Ulcers or Bleeds (not esophageal)0NR0NR
Metabolic
Hypercalciuria0NR119.8 (3.19, 819)
*

Significantly different.

Hazard ratio.

From: Results

Cover of Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report
Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report [Internet].
Comparative Effectiveness Reviews, No. 53.
Crandall CJ, Newberry SJ, Diamant A, et al.

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