Table 1Sensitivity and Specificity of Cytology and HPV Testing for Primary Screening and Triage of Abnormal Cytology Results

Screening or Triage TestSensitivity for CIN2+Specificity for <CIN2Delta of HPV Compared to Cytology in Same Study
Sensitivity (CIN2+)Specificity (CIN2+)
Cytology
EPC-QRS (2011)350.5690.945
Mayrand et al (2007)80.5640.973
Koliopoulos et al (2007)360.7270.919
 Range8,37,41-430.20–0.7720.847–0.990
Triage for ASC-US440.7620.638
 Range45-470.45–0.9560.475–0.756
HPV DNA (HC2)
EPC-QRS (2011)350.9640.9060.395-0.039
Mayrand et al (2007)80.9740.9430.41-0.03
Koliopoulos et al (2007)360.9480.860.221-0.059
 Range8,37,41-430.341–1.000.767–0.966
Triage for ASC-US440.8920.6410.130.003
 Range45-470.67–0.9760.31–0.672

From: Addendum

Cover of Screening for Cervical Cancer: A Decision Analysis for the U.S. Preventive Services Task Force
Screening for Cervical Cancer: A Decision Analysis for the U.S. Preventive Services Task Force [Internet].
Evidence Syntheses, No. 86s.
Kulasingam SL, Havrilesky L, Ghebre R, et al.

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