Table 1: Total volume of distribution estimates (VT) for [11C]GSK931145 in different regions of the pig brain after the animal was given blocking doses of unlabeled GSK565710.

Region of brainBaselineDose of unlabeled GSK565710 (μg/kg body weight)
110100
(VT; (ml/cm3)
Mesencephalon11.609.156.323.00
Cerebellum6.935.564.452.42
Cortex5.084.353.402.20

For complete data, see Passchier et al. (8).

From: 11C-Labeled GSK931145

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