Supporting Table 10.The kinetic properties of CAC

Reaction PalCar(IMS) + Car(MAT) ⇔ PalCar(MAT) + Car(IMS)
Mechanism Ping-pong Bi Bi25
Rate equation
Species Rat liver mitochondria
Parameter Class Notice
KmS1 0.6 x 10-3Class 0Ref. 25
KmS2 9.4 x 10-3Class 0Ref. 25
KmP1 43.4 x10-6Class 1 11.6 x 10-6, the value of Car/Car reaction
KmP2 0.4 x 10-3Class 1 1.2 x 10-3, the value of Car/Car reaction
KiS1 8.7x10-6Class 1 5.1 x 10-6, ref. 24
KiP2 250x10-6Class 1 510 x 10-6, ref. 24
Keq 243.3Class 3
KcF 1.22Class 2
KcR 1.08Class 10.92, ref. 24

Source for parameter estimation: Figure 4 with 13 mM acetylcarnitine in reference 24.

From: Dynamic Kinetic Modelling of Mitochondrial Energy Metabolism

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