Figure 11: . Potency Ratio vs.

Figure 11:

Potency Ratio vs. GM Potency. (A) Shows a case where the within-run variability is too large (MR= 0.8, RLs= (0.61-1.07), MSR= 3.54, and LsA= (0.23-2.84), and (B) shows a case where the LsA are outside the acceptable range because the Mean Ratio is too large, i.e., there is a tendency for the activity values in run 1 to be larger than in run 2 (MR= 2.01, RL= (1.75-2.32), MSR= 1.86, and LsA= (1.08-3.75). In both cases the reason(s) for these conditions should be investigated.

From: HTS Assay Validation

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Assay Guidance Manual [Internet].
Sittampalam GS, Coussens NP, Brimacombe K, et al., editors.
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