Figure 49-5. Cellular events of the induction, production, and action of interferon.

Figure 49-5Cellular events of the induction, production, and action of interferon

Inducers of interferon react with cells to depress the interferon gene(s) (A). This leads to the production of mRNA for interferon (B). The mRNA is translated into the interferon protein (C), which is secreted into the extracellular fluid(D), where it reacts with the membrane receptors of cells (E). The interferon-stimulated cells derepress genes (F) for effector proteins (AVP) that establish antiviral resistance and other cell changes. The activated cells also stimulate contacted cells (G) to produce AVP by a still unknown mechanism.

From: Chapter 49, Nonspecific Defenses

Cover of Medical Microbiology
Medical Microbiology. 4th edition.
Baron S, editor.
Copyright © 1996, The University of Texas Medical Branch at Galveston.

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