Table 7Sensitivity analyses on the cost per patient of using different sedation strategies compared with general anaesthesia in dental procedures in children

StrategyMean cost (base case)Success rate in base case (%)Success rate at which strategy becomes cost-saving compared to GA (%)Mean cost when success rate of sedation = 95%Mean cost when inductio n time of GA = 15minsMean cost when cost of N2O = £5
N20 + 02£2385259%£142£244£233
N20 + iv midazolam£2138075%£179£216£208
Sevoflurane + N20£2249090%£211£225£225
Sevoflurane + N20 + iv midazolam£24693*£242£247£240
GA£224100NA**£236£219

NA=not applicable.

*

not cost-saving even at 100%,

pt=patient,

N2O is used in combination with sevoflurane to maintain general anaesthesia.

**

Same as base case

From: Appendix F, Cost-effectiveness analysis

Cover of Sedation in Children and Young People
Sedation in Children and Young People: Sedation for Diagnostic and Therapeutic Procedures in Children and Young People [Internet].
NICE Clinical Guidelines, No. 112.
National Clinical Guideline Centre (UK).
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