Table 7Sensitivity analyses on the cost per patient of using different sedation strategies compared with general anaesthesia in dental procedures in children

StrategyMean cost (base case)Success rate in base case (%)Success rate at which strategy becomes cost-saving compared to GA (%)Mean cost when success rate of sedation = 95%Mean cost when inductio n time of GA = 15minsMean cost when cost of N2O = £5
N20 + 02£2385259%£142£244£233
N20 + iv midazolam£2138075%£179£216£208
Sevoflurane + N20£2249090%£211£225£225
Sevoflurane + N20 + iv midazolam£24693*£242£247£240

NA=not applicable.


not cost-saving even at 100%,


N2O is used in combination with sevoflurane to maintain general anaesthesia.


Same as base case

From: Appendix F, Cost-effectiveness analysis

Cover of Sedation in Children and Young People
Sedation in Children and Young People: Sedation for Diagnostic and Therapeutic Procedures in Children and Young People [Internet].
NICE Clinical Guidelines, No. 112.
National Clinical Guideline Centre (UK).
Copyright © 2010, National Clinical Guideline Centre.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

The rights of National Clinical Guideline Centre to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.