Review Protocol – Validated tools

Review questionFor children and young people under the age of 19 undergoing diagnostic and therapeutic procedures under sedation techniques, what validated tools should be used to support assessment?
ObjectivesTo establish what validated tools should be used to support clinicians to assess and decide whether the child:
  • should receive sedation OR
  • have some other kind of pain/anxiety management
  • Note: this is not about measuring how deep a child is sedated
Infants, children and young people under the age of 19 who are receiving sedation by any technique for diagnostic or therapeutic procedures including dental surgery and minor operations carried out under local anaesthesia.

InterventionValidated instrument/tools/equations/algorithms
ComparisonStandard care or head-to-head comparison with another validated instrument/tools/equations/algorithms
OutcomesOutcomes for efficacy for sedation sparing:
  1. Completion of procedure
Search strategyThe databases searched were Medline (from 1950 to Jan 18th 2010), Embase (from 1980 to Jan 18th 2010), The Cochrane Library (all dates available to 2009 Issue 4) and CINAHL (from 1982 to Jan 18th 2010).

Studies were restricted to English language only.

Searches were restricted using study design filters for RCTs, systematic reviews and observational studies
The review strategyThe review for drug efficacy will be based on RCT evidence only. Study details, methodology and results will be extracted into an Access database. Further statistical analysis and meta analysis will be conducted where possible and carried out in Rev Man as required. The methods of reviewing are detailed in Chapter 2. An evidence profile and quality assessment will be then entered into GRADE.

From: Appendix H, Review protocol form

Cover of Sedation in Children and Young People
Sedation in Children and Young People: Sedation for Diagnostic and Therapeutic Procedures in Children and Young People [Internet].
NICE Clinical Guidelines, No. 112.
National Clinical Guideline Centre (UK).
Copyright © 2010, National Clinical Guideline Centre.

Apart from any fair dealing for the purposes of research or private study, criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, no part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

The rights of National Clinical Guideline Centre to be identified as Author of this work have been asserted by them in accordance with the Copyright, Designs and Patents Act, 1988.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.