Table 6-2Complications of smallpox vaccination in the United States, 1968

NUMBER OF REPORTED CASES (deaths)
VACCINATION STATUS AND AGE (yr) ESTIMATED NUMBER OF VACCINATIONS Postvaccinal Encephalitis Progressive Vaccinnia Eczema Vaccinatum Generalized Vaccinia Accidental Infection Other
Primary vaccinations
<1 614,000 4 (3) 5 43 7 10
1–4 2,733,000 6 1 31 47 91 40
5–9 1,553,000 5 (1) 1 (1) 11 20 32 8
10–19 406,000 1(1) 3 5 3 1
≥20 288,000 1 2 7 13 4 5
Unknown 1 3 5 2
Total Revaccinations 5,594,000 16 (4) 5 (2) 58 131 142 66
<1
1–4 478,000 1 1 1
5–9 1,643,000 1 (1) 4 1 3 2
10–19 2,657,000 1 3
≥20 3,796,000 4 (1) 9 3 6
Total 8,574,000 6 (2) 8 10 7 9
Unvaccinated contacts 60 (1) 2 44 8
Total 14,168,000 16 (4) 11 (4) 126 (1) 143 193 83

From Lane JM, Ruben FL, Neff JM, Millar JD. Compliations of smallpox vaccination, 1968. National surveillance in the United States. N Engl J Med 281:1201–1208, 1969.

From: Active Immunization

Cover of Vaccines
Vaccines. 3rd edition.
Plotkin SA, Orenstein WA, editors.
Philadelphia: Saunders; 1999.
Copyright © 1999, W.B. Saunders Company.

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