Excerpt

This book is intended to serve both as a textbook for short bioinformatics courses and as a base for a self-teaching endeavor. It is divided in two parts: A. Bioinformatics Techniques and B. Case Studies. Each chapter of the first part addresses a specific problem in bioinformatics and consists of a theoretical part and of a detailed tutorial with practical applications of that theory using software freely available on the Internet. All of the authors who were selected for this part of the book have extensive experience in teaching Bioinformatics, either at WHO-TDR and other short-term courses, at universities around the world, or at both. In the second part, we invited renowned researchers to write chapters that represent up-to-date reviews of particular human diseases, including biological aspects and bioinformatics approaches that helped to solve specific problems.

Contents

• Preface
• A. Practical Bioinformatics
  • Chapter A01. Using Linux
    Alan Mitchell Durham and Marco Dimas Gubitoso.
    Created: May 1, 2006.
  • Chapter A02. Understanding Database Design
    João Eduardo Ferreira and Osvaldo Kotaro Takai.
    Created: September 12, 2007.
  • Chapter A05. Similarity Search
    João Carlos Setubal and Ruediger Braeuning.
    Created: February 10, 2006; Last Update: March 9, 2007.
  • Chapter A06. Protein Structure, Modelling and Applications
    Ardala Breda, Napoleão Fonseca Valadares, Osmar Norberto de Souza, and Richard Charles Garratt.
    Created: May 1, 2006; Last Update: September 14, 2007.
• B. Case Studies
  • Chapter B01. Control of Gene Expression in Plasmodium
    Mauro Ferreira de Azevedo and Hernando A. del Portillo.
    Created: July 17, 2006; Last Update: May 11, 2007.
  • Chapter B02. Leishmania Genomics: Where Do We Stand?
    Silvia R.B Uliana, Jeronimo C. Ruiz, and Angela K. Cruz.
    Created: October 12, 2006; Last Update: August 24, 2007.
  • Chapter B03. Tuberculosis, Leprosy, and Other Mycobacterioses
    Sylvia Cardoso Leão, Maria Isabel Romano, and Maria Jesus Garcia.
    Created: January 30, 2006; Last Update: September 24, 2007.
  • Chapter B04. Transgenic Vectors: Anopheles and Aedes
    Márcia Aparecida Sperança, Paulo Eduardo Martins Ribolla, and Margareth Lara Capurro.
    Created: December 6, 2006; Last Update: May 11, 2007.
  • Chapter B05. Proteomics Studies in Trypanosoma cruzi
    Ernesto S. Nakayasu and Igor C. Almeida.
    Created: October 12, 2006; Last Update: September 12, 2007.
  • Chapter B06. Expressed Sequence Tags (ESTs) and Gene Discovery: Schistosoma mansoni
    Ricardo DeMarco and Sergio Verjovski-Almeida.
    Created: October 12, 2006; Last Update: May 11, 2007.
  • Chapter B07. Alternative Splicing: Lessons from Cancer
    Sandro J. de Souza and Anamaria A. Camargo.
    Created: October 12, 2006; Last Update: September 17, 2007.