Table 3. Definition of TNM Stage II

Stage TNMDescriptionIllustration
IIT2a, N0, M0T2a = Tumor invades superficial muscularis propria (inner half).
Stage II bladder cancer; drawing shows the bladder, ureter, prostate, and urethra. Inset shows cancer in the inner lining of the bladder, the layer of connective tissue, and the muscle layers. Also shown is the layer of fat around the bladder.
N0 = No lymph node metastasis.
M0 = No distant metastasis.
T2b, N0, M0T2b = Tumor invades deep muscularis propria (outer half).
N0 = No lymph node metastasis.
M0 = No distant metastasis.

M = distant metastasis; N = regional lymph nodes; T = primary tumor.

Reprinted with permission from AJCC: Urinary bladder. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 497–505.

From: Bladder Cancer Treatment (PDQ®)

Cover of PDQ Cancer Information Summaries
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.

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