Table 7. Definitions of TNM Stage IIBa

StageTNMDescriptionIllustration
IIBT2b, N1, M0T2b = Tumor >5 cm but ≤7 cm in greatest dimension, or tumor with any of the following features: involves main bronchus, ≥2 cm distal to the carina; invades visceral pleura (PL1 or PL2); or is associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung.
Two-panel drawing of stage IIB non-small cell lung cancer. First panel shows cancer (more than 5 cm but not more than 7 cm), and cancer in the right main bronchus and lymph nodes; also shown are the trachea, bronchioles, and diaphragm. Inset shows cancer that has spread from the lung to the innermost layer of the lung lining; a rib is also shown. Second panel shows cancer (more than 7 cm), and cancer in the left main bronchus; also shown are the trachea, lymph nodes, bronchioles, and diaphragm. Top inset shows cancer that has spread from the lung through the lung lining and chest wall lining into the chest wall; a rib is also shown. Bottom inset shows the heart and cancer that has spread from the lung into the membrane around the heart.
N1 = Metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension.
M0 = No distant metastasis.
T3, N0, M0T3 = Tumor >7 cm or one that directly invades any of the following: parietal pleural (PL3) chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, or parietal pericardium or tumor in the main bronchus (<2 cm distal to the carinab but without involvement of the carina) or associated atelectasis or obstructive pneumonitis of the entire lung or separate tumor nodule(s) in the same lobe.b
N0 = No regional lymph node metastasis.
M0 = No distant metastasis.

aReprinted with permission from AJCC: Lung. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 253-70.

bThe uncommon superficial spreading of the tumor of any size with its invasive component limited to the bronchial wall, which may extend proximally to the main bronchus, is also classified as T1a.

From: Non-Small Cell Lung Cancer Treatment (PDQ®)

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PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.

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