Table 1A family of CUGBP1 and ETR-3 like factors (CELF) bind to bruno element and regulate cTnT splicing

  % similarity Binding Splicing
CELFa BRUNOLb w/ CUGBP1 brunob cTNTa activity (cTNT)a
CUGBP1BRUNOL2+++
ETR-3BRUNOL378%+++
CELF3 BRUNOL144%NDND+
CELF4BRUNOL4 42%ND++
CELF5 BRUNOL539%NDND+

a(Ladd et al. 2001).

b(Good et al. 2000). ND, not determined.

From: Myotonic Dystrophy: Discussion of Molecular Basis

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