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InformedHealth.org

This resource includes articles, fact sheets, and research summaries from Informed Health Online, the patient-centered health information portal of Germany's national health information website, Institute for Quality and Efficiency in Health Care.

Contents

Topics

Allergic contact dermatitis

Allergies

Drugs assessed by IQWiG

Infertility

Measles

Osteoarthritis

Pregnancy and birth

Rubella (German measles)

Scarlet fever

Styes and chalazia (inflammation of the eyelid)

Vocal nodules

Wrist injuries

In brief

The human body

Treatments and diagnostic tests

Early-benefit assessment of medications

Abemaciclib (EU: Verzenios, U.S.: Verzenio) and aromatase inhibitors for the treatment of advanced breast cancer
Abiraterone acetate (Zytiga) for the treatment of metastatic prostate cancer
Alirocumab (Praluent) for the treatment of hypercholesterolemia and mixed dyslipidemia
Andexanet alfa (EU: Ondexxya, U.S.: Andexxa) for the treatment of major bleeding
Apalutamide (Erleada) for the treatment of metastatic prostate cancer
Apalutamide (Erleada) for the treatment of prostate cancer
Apremilast (Otezla) for the treatment of aphthous ulcers in Behçet's disease
Asfotase alfa (Strensiq) for the treatment of hypophosphatasia
Atezolizumab (Tecentriq) for the treatment of advanced bladder cancer (urothelial carcinoma)
Atezolizumab (Tecentriq) for the treatment of advanced breast cancer
Atezolizumab (Tecentriq) for the treatment of advanced lung cancer
Avelumab (Bavencio) for the treatment of metastatic Merkel cell carcinoma
Axitinib (Inlyta) for renal cell cancer
Belimumab (Benlysta) for the treatment of systemic lupus erythematosus in children and teenagers
Benralizumab (Fasenra) for the treatment of severe asthma
Bezlotoxumab (Zinplava) for the treatment of Clostridium difficile infections
Binimetinib (Mektovi) and encorafenib (Braftovi) for the treatment of advanced melanoma
Bosutinib (Bosulif) for the treatment of chronic myeloid leukemia
Brigatinib (Alunbrig) for the treatment of advanced non-small-cell lung cancer
Brivaracetam (Briviact) for the treatment of epilepsy
Brodalumab (EU: Kyntheum, U.S.: Siliq) for the treatment of psoriasis
Cabozantinib (Cabometyx) for the treatment of advanced hepatocellular carcinoma (liver cancer)
Cannabis sativa (Sativex) for the treatment of spasticity due to multiple sclerosis
Carfilzomib (Kyprolis) for the treatment of multiple myeloma
Cariprazine (Reagila) for the treatment of schizophrenia
Cemiplimab (Libtayo) for the treatment of advanced non-melanoma skin cancer
Ceritinib (Zykadia) for the treatment of advanced lung cancer
Cladribine (Mavenclad) for the treatment of multiple sclerosis
Cobicistat (Tybost) for the treatment of HIV-1 infection in teenagers
Crizotinib (Xalkori) for advanced lung cancer
Dacomitinib (Vizimpro) for the treatment of advanced lung cancer
Damoctocog alfa pegol (Jivi) for the treatment of hemophilia A
Dapagliflozin (EU: Forxiga, U.S.: Farxiga) for the treatment of type 2 diabetes
Darolutamide (Nubeqa) for the treatment of prostate cancer
Darunavir in a fixed-dose combination (Symtuza) for the treatment of HIV
Dimethyl fumarate (Skilarence) for the treatment of psoriasis
Dolutegravir / rilpivirine (Juluca) for the treatment of HIV
Doravirine (Pifeltro) for the treatment of HIV
Doravirine / lamivudine / tenofovir disoproxil fumarate (Delstrigo) for the treatment of HIV
Dupilumab (Dupixent) for the treatment of chronic rhinosinusitis with nasal polyps
Dupilumab (Dupixent) for the treatment of severe asthma
Durvalumab (Imfinzi) for the treatment of advanced lung cancer
Elbasvir / grazoprevir (Zepatier) for hepatitis C
Elotuzumab (Empliciti) for multiple myeloma
Elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil (Stribild) for the treatment of HIV in teenagers
Emicizumab (Hemlibra) for the treatment of hemophilia A
Empagliflozin / Metformin (Synjardy) for type 2 diabetes
Encorafenib (Braftovi) for the treatment of metastatic colorectal cancer (bowel cancer)
Erenumab (Aimovig) for the prevention of migraine
Etelcalcetide (Parsabiv) for the treatment of hyperparathyroidism (overactive parathyroid gland)
Evolocumab (Repatha) for the treatment of hypercholesterolemia and mixed dyslipidemia
Fixed combination of saxagliptin and metformin (Komboglyze) for the treatment of type 2 diabetes
Fixed-dose combination ceftolozane / tazobactam (Zerbaxa) for the treatment of complicated intra-abdominal infections
Fixed-dose combination ceftolozane / tazobactam (Zerbaxa) for the treatment of complicated urinary tract infections and acute pyelonephritis
Fixed-dose combination of ceftolozane / tazobactam (Zerbaxa) for the treatment of hospital-acquired pneumonia
Fixed-dose combination of dapagliflozin and metformin (Xigduo) for the treatment of type 2 diabetes
Fixed-dose combination of empagliflozin / linagliptin (Glyxambi) for the treatment of type 2 diabetes
Fixed-dose combination of ertugliflozin and sitagliptin (Steglujan) for the treatment of type 2 diabetes
Fixed-dose combination of fluticasone furoate / umeclidinium / vilanterol (Trelegy Ellipta) for the treatment of COPD
Fixed-dose combination of insulin glargine / lixisenatide (Suliqua) for the treatment of type 2 diabetes
Fixed-dose combination of lumacaftor / ivacaftor (Orkambi) for the treatment of cystic fibrosis in children
Fostamatinib (Tavlesse) for the treatment of chronic immune thrombocytopenia
Fremanezumab (Ajovy) for the prevention of migraine
Galcanezumab (Emgality) for the treatment of migraine
Glecaprevir / pibrentasvir (Maviret) for the treatment of chronic hepatitis C
Glycopyrronium bromide (Sialanar) for the treatment of chronic pathological drooling
Hydrocortisone (Alkindi) for the treatment of adrenal insufficiency
Ibrutinib (Imbruvica) for the treatment of Waldenström's macroglobulinemia
Idelalisib (Zydelig) for chronic lymphocytic leukemia (CLL)
Ingenol mebutate (Picato) for actinic keratosis
Insulin degludec / liraglutide (Xultophy) for type 2 diabetes in adults
Ixekizumab (Taltz) for the treatment of axial spondyloarthritis
Larotrectinib (Vitrakvi) for the treatment of advanced tumors
Ledipasvir / sofosbuvir (Harvoni) for the treatment of chronic hepatitis C in teenagers
Lenvatinib (EU: Kisplyx, U.S.: Lenvima) for advanced renal cell cancer
Lenvatinib (Lenvima) for the treatment of advanced thyroid cancer
Lenvatinib (Lenvima) for the treatment of hepatocellular carcinoma (liver cancer)
Lisdexamfetamine (Elvanse / Elvanse Adult, Vyvanse) for the treatment of ADHD
Lonoctocog alfa (Afstyla) for hemophilia A
Lorlatinib (Lorviqua, Lorbrena) for the treatment of advanced lung cancer
Macitentan (Opsumit) for pulmonary arterial hypertension
Melatonin (Slenyto) for the treatment of insomnia
Mepolizumab (Nucala) for the treatment of severe asthma
Naldemedine (Rizmoic) for the treatment of opioid-induced constipation
Nalmefene (Selincro) for alcohol dependency
Neratinib (Nerlynx) for the treatment of breast cancer
Nintedanib (Ofev) for the treatment of idiopathic pulmonary fibrosis
Niraparib (Zejula) for the treatment of ovarian cancer
Nivolumab (Opdivo) for Hodgkin's lymphoma
Nivolumab (Opdivo) for head and neck cancer
Nivolumab (Opdivo) for the treatment of advanced urothelial carcinoma
Nonacog beta pegol (Refixia) for the treatment of hemophilia B
Ocriplasmin (Jetrea) for the treatment of vitreomacular traction
Olaparib (Lynparza) for the treatment of advanced breast cancer
Opicapone (Ongentys) for Parkinson's disease
Osimertinib (Tagrisso) for the treatment of advanced lung cancer with a T790M mutation
Osimertinib (Tagrisso) for the treatment of advanced lung cancer with activating EGFR mutations
Palbociclib (Ibrance) for the treatment of advanced breast cancer
Patiromer (Veltassa) for the treatment of hyperkalemia
Pembrolizumab (Keytruda) for the treatment of Hodgkin’s lymphoma
Pembrolizumab (Keytruda) for the treatment of advanced bladder cancer (urothelial carcinoma)
Perampanel (Fycompa) for the treatment of epilepsy
Pomalidomide (EU: Imnovid, U.S.: Pomalyst) for the treatment of multiple myeloma
Radium-223 dichloride (Xofigo) for the treatment of advanced prostate cancer
Ramucirumab (Cyramza) for the treatment of advanced liver cancer
Ramucirumab (Cyramza) for the treatment of metastatic lung cancer
Ravulizumab (Ultomiris) for the treatment of atypical hemolytic uremic syndrome
Reslizumab (EU: Cinqaero, U.S.: Cinqair) for severe asthma
Riociguat (Adempas) for the treatment of chronic thromboembolic pulmonary hypertension (high blood pressure)
Risankizumab (Skyrizi) for the treatment of psoriasis
Rolapitant (EU: Varuby, U.S.: Varubi) for the prevention of nausea and vomiting in chemotherapy
Romosozumab (Evenity) for the treatment of osteoporosis
Ropeginterferon alfa-2b (Besremi) for the treatment of polycythemia vera
Rucaparib (Rubraca) for the treatment of advanced ovarian cancer
Rurioctocog alfa pegol (Adynovi) for the treatment of hemophilia A
Sarilumab (Kevzara) for the treatment of rheumatoid arthritis
Semaglutide (Ozempic) for the treatment of type 2 diabetes
Siponimod (Mayzent) for the treatment of multiple sclerosis
Solriamfetol (Sunosi) for the treatment of narcolepsy
Sonidegib (Odomzo) for the treatment of non-melanoma skin cancer
Talazoparib (Talzenna) for the treatment of advanced breast cancer
Tenofovir alafenamide (Vemlidy) for the treatment of chronic hepatitis B
Tezacaftor / ivacaftor (Symkevi) for the treatment of cystic fibrosis
The fixed-dose combination trifluridine / tipiracil (Lonsurf) for the treatment of advanced gastric (stomach) cancer
Tildrakizumab (EU: Ilumetri, U.S.: Ilumya) for the treatment of psoriasis
Tivozanib (Fotivda) for the treatment of advanced renal cell cancer
Tofacitinib (Xeljanz) for the treatment of psoriasis with inflammation of the joints (psoriatic arthritis)
Tofacitinib (Xeljanz) for the treatment of rheumatoid arthritis
Tofacitinib (Xeljanz) for the treatment of ulcerative colitis
Trametinib (Mekinist) plus dabrafenib (Tafinlar) for the treatment of advanced lung cancer
Trastuzumab emtansine (Kadcyla) for the treatment of early-stage breast cancer
Trifluridine / tipiracil (Lonsurf) for the treatment of metastatic colorectal cancer
Turoctocog alfa pegol (Esperoct) for the treatment of hemophilia A
Vandetanib (Caprelsa) for aggressive thyroid cancer
Venetoclax (EU: Venclyxto, U.S.: Venclexta) for the treatment of chronic lymphocytic leukemia (CLL)
© IQWiG (Institute for Quality and Efficiency in Health Care)
Bookshelf ID: NBK65083

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