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InformedHealth.org

This resource includes articles, fact sheets, and research summaries from Informed Health Online, the patient-centered health information portal of Germany's national health information website, Institute for Quality and Efficiency in Health Care.

Contents

Topics

Allergic contact dermatitis

Allergies

Drugs assessed by IQWiG

Infertility

Scarlet fever

Vocal nodules

In brief

The human body

Treatments and diagnostic tests

Early-benefit assessment of medications

Abemaciclib (EU: Verzenios, U.S.: Verzenio) and aromatase inhibitors for the treatment of advanced breast cancer
Abiraterone acetate (Zytiga) for the treatment of metastatic prostate cancer
Afatinib (Giotrif) for advanced squamous cell lung cancer
Aflibercept (Eylea) for myopic choroidal neovascularization
Alirocumab (Praluent) for the treatment of hypercholesterolemia and mixed dyslipidemia
Apalutamide (Erleada) for the treatment of prostate cancer
Atezolizumab (Tecentriq) for the treatment of advanced bladder cancer (urothelial carcinoma)
Atezolizumab (Tecentriq) for the treatment of advanced lung cancer
Axitinib (Inlyta) for renal cell cancer
Belatacept (Nulojix) following a kidney transplant
Benralizumab (Fasenra) for the treatment of severe asthma
Bezlotoxumab (Zinplava) for the treatment of Clostridium difficile infections
Binimetinib (Mektovi) and encorafenib (Braftovi) for the treatment of advanced melanoma
Bosutinib (Bosulif) for the treatment of chronic myeloid leukemia
Brigatinib (Alunbrig) for the treatment of advanced non-small-cell lung cancer
Brivaracetam (Briviact) for the treatment of epilepsy
Brodalumab (EU: Kyntheum, U.S.: Siliq) for the treatment of psoriasis
Cabozantinib (Cabometyx) for the treatment of advanced hepatocellular carcinoma (liver cancer)
Cannabis sativa (Sativex) for the treatment of spasticity due to multiple sclerosis
Carfilzomib (Kyprolis) for the treatment of multiple myeloma
Cariprazine (Reagila) for the treatment of schizophrenia
Ceritinib (Zykadia) for the treatment of advanced lung cancer
Cladribine (Mavenclad) for the treatment of multiple sclerosis
Cobimetinib (Cotellic) for melanoma
Crizotinib (Xalkori) for advanced lung cancer
Damoctocog alfa pegol (Jivi) for the treatment of hemophilia A
Dapagliflozin (U.S.: Farxiga, EU: Forxiga) for the treatment of type 2 diabetes
Darunavir in a fixed-dose combination (Symtuza) for the treatment of HIV
Dimethyl fumarate (Skilarence) for the treatment of psoriasis
Dolutegravir / rilpivirine (Juluca) for the treatment of HIV
Doravirine (Pifeltro) for the treatment of HIV
Doravirine / lamivudine / tenofovir disoproxil fumarate (Delstrigo) for the treatment of HIV
Dupilumab (Dupixent) for the treatment of eczema
Durvalumab (Imfinzi) for the treatment of advanced lung cancer
Elbasvir / grazoprevir (Zepatier) for hepatitis C
Elotuzumab (Empliciti) for multiple myeloma
Elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil (Stribild) for the treatment of HIV in teenagers
Emicizumab (Hemlibra) for the treatment of hemophilia A
Empagliflozin / Metformin (Synjardy) for type 2 diabetes
Emtricitabine / rilpivirine / tenofovir alafenamide (Odefsey) for HIV
Erenumab (Aimovig) for the prevention of migraine
Eribulin (Halaven) for liposarcoma
Etelcalcetide (Parsabiv) for the treatment of hyperparathyroidism (overactive parathyroid gland)
Evolocumab (Repatha) for the treatment of hypercholesterolemia and mixed dyslipidemia
Fixed combination of saxagliptin and metformin (Komboglyze) for the treatment of type 2 diabetes
Fixed combination of sitagliptin and metformin (Janumet or Velmetia) for type 2 diabetes
Fixed-dose combination of dapagliflozin and metformin (Xigduo) for the treatment of type 2 diabetes
Fixed-dose combination of ertugliflozin and sitagliptin (Steglujan) for the treatment of type 2 diabetes
Fixed-dose combination of fluticasone furoate / umeclidinium / vilanterol (Trelegy Ellipta) for the treatment of COPD
Fixed-dose combination of insulin glargine / lixisenatide (Suliqua) for the treatment of type 2 diabetes
Fixed-dose combination of lumacaftor / ivacaftor (Orkambi) for the treatment of cystic fibrosis in children
Glecaprevir / pibrentasvir (Maviret) for the treatment of chronic hepatitis C
Glycopyrronium bromide (Sialanar) for the treatment of chronic pathological drooling
Hydrocortisone (Alkindi) for the treatment of adrenal insufficiency
Ibrutinib (Imbruvica) for Waldenström's macroglobulinemia
Ibrutinib (trade name: Imbruvica) for mantle cell lymphoma
Idelalisib (Zydelig) for chronic lymphocytic leukemia (CLL)
Indacaterol and glycopyrronium (Ultibro Breezhaler Xoterna Breezhaler) for chronic obstructive pulmonary disease (COPD)
Ingenol mebutate (Picato) for actinic keratosis
Insulin degludec (Tresiba) for diabetes in teenagers and children
Insulin degludec / liraglutide (Xultophy) for type 2 diabetes in adults
Ledipasvir / sofosbuvir (Harvoni) for the treatment of chronic hepatitis C in teenagers
Lenvatinib (EU: Kisplyx, USA: Lenvima) for advanced renal cell cancer
Lenvatinib (Lenvima) for the treatment of advanced thyroid cancer
Lenvatinib (Lenvima) for the treatment of hepatocellular carcinoma (liver cancer)
Lomitapide (Lojuxta, Juxtapid) for familial hypercholesterolemia
Lonoctocog alfa (Afstyla) for hemophilia A
Lurasidone (Latuda) for schizophrenia
Macitentan (Opsumit) for pulmonary arterial hypertension
Melatonin (Slenyto) for the treatment of insomnia
Mepolizumab (Nucala) for the treatment of severe asthma
Nalmefene (Selincro) for alcohol dependency
Necitumumab (Portrazza) for advanced lung cancer
Netupitant / palonosetron (Akynzeo) for chemotherapy-related nausea and vomiting
Nintedanib (Vargatef) for advanced lung cancer
Nivolumab (Opdivo) for Hodgkin's lymphoma
Nivolumab (Opdivo) for advanced renal cell cancer
Nivolumab (Opdivo) for head and neck cancer
Nivolumab (Opdivo) for the treatment of advanced urothelial carcinoma
Nonacog beta pegol (Refixia) for the treatment of hemophilia B
Ocriplasmin (Jetrea) for the treatment of vitreomacular traction
Olaparib (Lynparza) for the treatment of ovarian cancer
Opicapone (Ongentys) for Parkinson's disease
Osimertinib (Tagrisso) for the treatment of advanced lung cancer with a T790M mutation
Osimertinib (Tagrisso) for the treatment of advanced lung cancer with activating EGFR mutations
Ospemifene (EU: Senshio, US: Osphena/Ophena) for vaginal atrophy
Palbociclib (Ibrance) for the treatment of advanced breast cancer
Patiromer (Veltassa) for the treatment of hyperkalemia
Pembrolizumab (Keytruda) for the treatment of Hodgkin’s lymphoma
Pembrolizumab (Keytruda) for the treatment of advanced bladder cancer (urothelial carcinoma)
Pembrolizumab (Keytruda) for the treatment of head and neck cancer
Perampanel (Fycompa) for the treatment of epilepsy
Propranolol (Hemangiol) for hemangioma in infants
Ramucirumab (Cyramza) for advanced lung cancer
Ramucirumab (Cyramza) for advanced stomach cancer
Reslizumab (EU: Cinqaero, U.S.: Cinqair) for severe asthma
Rolapitant (EU: Varuby, U.S.: Varubi) for the prevention of nausea and vomiting in chemotherapy
Rurioctocog alfa pegol (Adynovi) for the treatment of hemophilia A
Ruxolitinib (Jakavi) for myelofibrosis
Ruxolitinib (Jakavi) for polycythaemia vera
Safinamide (Xadago) for Parkinson's disease
Sarilumab (Kevzara) for the treatment of rheumatoid arthritis
Secukinumab (Cosentyx) for ankylosing spondylitis
Selexipag (Uptravi) for pulmonary arterial hypertension
Semaglutide (Ozempic) for the treatment of type 2 diabetes
Simoctocog alfa (Nuwiq) for hemophilia A
Sipuleucel-T (Provenge) for metastatic prostate cancer
Sonidegib (Odomzo) for the treatment of non-melanoma skin cancer
Sucroferric oxyhydroxide (Velphoro) for chronic kidney disease
Talimogene laherparepvec (Imlygic) for melanoma
Tenofovir alafenamide (Vemlidy) for the treatment of chronic hepatitis B
Ticagrelor (trade name EU: Brilique, US: Brilinta) for people at high risk of a stroke or heart attack
Tildrakizumab (EU: Ilumetri, U.S.: Ilumya) for the treatment of psoriasis
Tivozanib (Fotivda) for the treatment of advanced renal cell cancer
Tofacitinib (Xeljanz) for the treatment of psoriasis with inflammation of the joints (psoriatic arthritis)
Tofacitinib (Xeljanz) for the treatment of rheumatoid arthritis
Tofacitinib (Xeljanz) for the treatment of ulcerative colitis
Trametinib (Mekinist) plus dabrafenib (Tafinlar) for the treatment of advanced lung cancer
Trifluridine / tipiracil (Lonsurf) for metastatic colorectal cancer
Umeclidinium (Incruse) for chronic obstructive pulmonary disease (COPD)
Umeclidinium and vilanterol (Anoro) for chronic obstructive pulmonary disease (COPD)
Vandetanib (Caprelsa) for aggressive thyroid cancer
Venetoclax (EU: Venclyxto, U.S.: Venclexta) for the treatment of chronic lymphocytic leukemia (CLL)
Vildagliptin (Galvus, Jalra) for type 2 diabetes
Vismodegib (Erivedge) for basal cell carcinoma
Vortioxetine (Brintellix) for depression
© IQWiG (Institute for Quality and Efficiency in Health Care)
Bookshelf ID: NBK65083

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