Table 10. Changes in bone mass following surgery for PHPTa

ReferenceYearStudy designNo. of subjectsMethod and bone measuredAverage increase in BMD following surgery (percent)
Mole(143)1992Prospective 4 yr43SPA-radius3
Warner(144)1991Cohort followup 2 yr40SPA-radius2-2.5
Martin(145)1990Case series 40 mo (mean)71SPA-radius5-6
Mautalen(146)1986Prospective 20.4 mo (avg)14SPA-radius8
Hesp(147)


1987


Prospective 17 mo


18


QCT-radius
Distal
Mid

12
No further loss
Alhava(173)

1988

Prospective 5 yr

45

QCT
Distal radius

10
Silverberg(174)


1995


Prospective 4 yr


34


DXA-spine
Femoral neck
Radius
12.8 ± 2.8 (P < 0.001)
12.7 ± 3.8 (P < 0.01)
4.0 ± 1.5 (P < 0.05)

a Includes patients who are asymptomatic or have mild symptoms.

Abbreviations: BMD = bone mass density.

From: Bone Densitometry: Patients with Asymptomatic Primary Hyperparathyroidism

Cover of AHCPR Health Technology Assessments
AHCPR Health Technology Assessments.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.