Table 1Transient transfection experiments

DNAAbnormalKaryotypes Total% Abnormal

Lymphoblastoid cells were transiently transfected with the indicated vectors, allowing the expression of different presenilin proteins. Karyotype analysis was carried out 72 hours after transfection and the number of abnormal karyotypes counted.

From: Cell Cycle and Chromosome Segregation Defects in Alzheimer's Disease

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