Figure 3. Restoration of peroxisomal membrane biogenesis and matrix protein import in a human cell.

Figure 3

Restoration of peroxisomal membrane biogenesis and matrix protein import in a human cell. Subcellular localization of GFP coupled to a PTS1-peptide in a peroxisome-deficient (ΔPEX16) human fibroblast (A), and 48 hr after a (ΔPEX16) cell was complemented by microinjection of plasmids containing PEX16 (B). Expression of PEX16 resulted in the de novo biogenesis of peroxisomes-including membrane lipid and protein assembly and matrix protein import.

From: The Biogenesis and Cell Biology of Peroxisomes in Human Health and Disease

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