Box 2Assessment of proteinuria

  • Use an automated reagent-strip reading device or a spot urinary protein:creatinine ratio to estimate proteinuria in secondary care.
  • If an automated reagent-strip reading device shows proteinuria ≥ 1+, use a spot urinary protein:creatinine ratio or 24-hour urine collection to quantify proteinuria.
  • Diagnose significant proteinuria if urinary protein:creatinine ratio > 30 mg/mmol or a validated 24-hour urine collection result shows > 300 mg protein.
  • Where 24-hour urine collection is used to quantify proteinuria, there should be a recognised method of evaluating completeness of the sample.

From: 1, Summary of recommendations and care pathway

Cover of Hypertension in Pregnancy
Hypertension in Pregnancy: The Management of Hypertensive Disorders During Pregnancy.
NICE Clinical Guidelines, No. 107.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2010 Aug.
Copyright © 2011, Royal College of Obstetricians and Gynaecologists.

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