TABLE 16-1bMeans or Proportions of CRP Systolic Blood Pressure, Hypertension, and Potential Confounders by 1059G/C Genotype

Means or Proportions by Genotype
GGGC or CCP
CRP (mg/L log scale)a1.811.39< 0.001
Hypertension (%)53.353.10.95
Body mass index (kg/m2)27.527.80.29
High-density lipoprotein cholesterol (mmol/l)1.671.650.38
Lifecourse socioeconomic position score4.354.420.53
Doctor diagnosed diabetes (%)4.74.50.80
Current smoker (%)11.29.30.24
Physically inactive (%)18.918.91.0
Moderate alcohol consumption (%)18.619.80.56
a

Geometric means and proportionate (%) change for a doubling of CRP.

CRP = C-reactive protein.

From: 16, Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies

Cover of Biosocial Surveys
Biosocial Surveys.
National Research Council (US) Committee on Advances in Collecting and Utilizing Biological Indicators and Genetic Information in Social Science Surveys; Weinstein M, Vaupel JW, Wachter KW, editors.
Washington (DC): National Academies Press (US); 2008.
Copyright © 2008, National Academy of Sciences.

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