Excluded trialsExclusion code
Active-control trials
Karlsson M, Berggren A-C. Efficacy and safety of low-dose transdermal buprenorphine patches (5, 10, and 20 microg/h) versus prolonged-release tramadol tablets (75, 100, 150, and 200 mg) in patients with chronic osteoarthritis pain: a 12-week, randomized, open-label, controlled, parallel-group noninferiority study. Clin. Ther. Mar 2009;31(3):503–5133
Shram MJ, Sathyan G, Khanna S, et al. Evaluation of the abuse potential of extended release hydromorphone versus immediate release hydromorphone. J. Clin. Psychopharmacol. Feb 2010;30(1):25–33.4
Placebo-controlled trials
Corsinovi L, Martinelli E, Fonte G, et al. Efficacy of oxycodone/acetaminophen and codeine/acetaminophen vs. conventional therapy in elderly women with persistent, moderate to severe osteoarthritis-related pain. Arch. Gerontol. Geriatr. 2009;49:378–382.3
Vondrackova D, Leyendecker P, Meissner W, et al. Analgesic efficacy and safety of oxycodone in combination with naloxone as prolonged release tablets in patients with moderate to severe chronic pain. Journal of Pain. Dec 2008;9(12):1144–11543

From: Appendix D, Excluded trials Update 6

Cover of Drug Class Review: Long-Acting Opioid Analgesics
Drug Class Review: Long-Acting Opioid Analgesics: Final Update 6 Report [Internet].
Carson S, Thakurta S, Low A, et al.
Portland (OR): Oregon Health & Science University; 2011 Jul.
Copyright © 2011 by Oregon Health & Science University.

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