ClinicalThere is no statistically significant difference in the number of patients with visual field progression at 2 to 6 years follow up. (LOW QUALITY)
Beta-blockers are more effective than no treatment in reducing IOP from baseline at 2 to 6 years follow up. However, there is significant unexplained statistical heterogeneity within the results. This evidence relates to patients with ocular hypertension. (VERY LOW QUALITY)
There is no statistically significant difference in the number of patients with an uncontrolled intraocular pressure of over 30mmHg at 2 to 10 years follow up. This evidence relates to patients with ocular hypertension. (LOW QUALITY)
There were no studies which reported the number of patients with an acceptable IOP.
There is no statistically significant difference in the number of patients experiencing a respiratory or cardiovascular adverse event at 5 years follow up. (LOW QUALITY)
EconomicBeta-blockers are more cost-effective than no treatment for any stage of COAG. This evidence has minor limitations and direct applicability.

From: 8, Treatment of chronic open angle glaucoma

Cover of Glaucoma
Glaucoma: Diagnosis and Management of Chronic Open Angle Glaucoma and Ocular Hypertension.
NICE Clinical Guidelines, No. 85.
National Collaborating Centre for Acute Care (UK).
Copyright © 2009, National Collaborating Centre for Acute Care.

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