Table 2Definitions of the grades of overall strength of evidence31

GradeDefinition
HighHigh confidence that the evidence reflects the true effect. Further research is very unlikely to change our confidence in the estimate of effect.
ModerateModerate confidence that the evidence reflects the true effect. Further research may change our confidence in the estimate of the effect and may change the estimate.
LowLow confidence that the evidence reflects the true effect. Further research is likely to change our confidence in the estimate of the effect and is likely to change the estimate.
InsufficientEvidence either is unavailable or does not permit estimation of an effect.

From: Methods

Cover of Drug Class Review: Neuropathic Pain
Drug Class Review: Neuropathic Pain: Final Update 1 Report [Internet].
Selph S, Carson S, Fu R, et al.
Portland (OR): Oregon Health & Science University; 2011 Jun.
Copyright © 2011 by Oregon Health & Science University.

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