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Selph S, Carson S, Fu R, et al. Drug Class Review: Neuropathic Pain: Final Update 1 Report [Internet]. Portland (OR): Oregon Health & Science University; 2011 Jun.

Cover of Drug Class Review: Neuropathic Pain

Drug Class Review: Neuropathic Pain: Final Update 1 Report [Internet].

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Evidence Tables

Evidence Table 1. Update 1: Data abstraction of head-to-head trials

Evidence Table 2. Update 1: Data abstraction of placebo-controlled trials

Evidence Table 3. Update 1: Quality assessment of trials

Evidence Table 4. Update 1: Quality assessment of observational studies

Evidence Table 5. Update 1: Data abstraction of systematic reviews

Evidence Table 6. Update 1: Quality assessment of systematic reviews

Evidence Table 7. Original report: Data abstraction of pregabalin, gabapentin, serotonin-norepinephrine reuptake inhibitors, and topical lidocaine (patch or gel)

Evidence Table 8. Original report: Data abstraction of other antiepileptics and tricyclic antidepressants

Evidence Table 9. Original report: Quality assessment of included trials

Abbreviations used in evidence tables

ACT

Active-control trial

AE

Adverse event

AED

Anti-epileptic drugs

ANCOVA

Analysis of covariance

ANOVA

Analysis of variance

bid

Twice daily

BMI

Body mass index

BPI

Brief Pain Inventory

CCT

Controlled clinical trial

CES-D

Center for Epidemiologic Studies-Depression Scale

CESD-SF

The Center for Epidemiologic Studies Depression Scale-Short Form

CGIC

Clinical Global Impression of Change

CI

Confidence interval

CLcr

Creatinine clearance rates

CNS

Central nervous system

COX-2

Cyclooxygenase-2 inhibitor

CPSP

Central post-stroke pain

CR

Controlled release

CRPS

Complex regional pain syndrome

CV

Cardiovascular

CVS

Cardiovascular system

d

Day

DAAC

Duration Adjusted Average Change

DB

Double-blind

dL

Deciliter

DM

Diabetes Mellitus

DPN

Diabetic peripheral neuropathic pain

DPRS

Daily Pain Rating Scale

ECG

Electrocardiogram

EEG

Electroencephalogram

EF

Ejection fraction

EQ-5D

European Quality of Life-5 Dimensions

ER

Extended release

FDA

US Food and Drug Administration

FU

Follow-up

g

Gram

GATE

Global Assessment of Therapeutic Effect

GI

Gastrointestinal

GP

General practitioner

h

Hour

HADS

Hospital Anxiety and Depression Scale

HbA1c

Hemoglobin A1c

HDL-C

High density lipoprotein cholesterol

HIV-DSP

HIV associated distal sensory polyneuropathy

HMO

Health maintenance organization

HR

Hazard ratio

HRQOL

Health-related quality of life

ICD-10

International Classification of Diseases, Tenth Revision

ICD-9

International Classification of Diseases, Ninth Revision

IR

Immediate release

ITT

Intent-to-treat

L

Liter

LA

Long acting

LANSS

Leeds assessment of neuropathic symptoms and signs questionnaire

LDL-C

Low-density lipoprotein cholesterol

LOCF

Last Observation Carried Forward

LS means

Least squares means

MANCOVA

Multivariate analysis of covariance

mcg

Microgram

MDD

Major depressive disorder

mg

Milligram

min

Minute

mL

Milliliter

MMRM

Mixed-model repeated measures model

MNSI

Michigan Neuropathy Screening Instrument

mo

Month

MOS-Sleep

Medical Outcome Study Sleep Scale

MPQ

McGill Pain Questionnaire

MS

Multiple sclerosis

MSQOL-54

54-item Multiple Sclerosis Quality-of-Life Questionnaire

N

Sample size (entire sample)

n

Subgroup sample size

NA

Not applicable

NCI-CTC

National Cancer Institute-Common Toxicity Criteria

NP

Neuropathic pain

NPRS

Numeric Pain Rating Scale

NPS

Neuropathic Pain Scale

NPSI

Neuropathic Pain Symptom Inventory

NR

Not reported

NS

Not significant

NSD

No significant difference

OR

Odds ratio

P

P value

P

Placebo

PCT

Placebo-controlled trial

PGIC

Patient Global Impression of Change

PHN

postherpetic neuralgia

PMPS

postmastectomy pain syndrome

POMS

Profile of Mood State

PP

Primary Progressive

PPI

Present Pain Intensity index

PPY

Per person year

QANeP

Quantitative Assessments of Neuropathic Pain

qd

Once daily

QOL

Quality of life

RCT

Randomized controlled trial

RR

Relapse-remitting

RR

Relative risk

SB

Single-blind

SCI

Spinal cord injury

SD

Standard deviation

SDLP

Standard deviation of lateral position

SE

Standard error

SF-MPQ

Short Form McGill Pain Questionnaire

SP

Secondary Progressive

SR

Sustained release

STAI

Spielberger State-Trait Anxiety Scales

tid

Three times daily

URTI

Upper respiratory tract infection

VAS

Visual analog scale

vs.

Compared with (versus)

WD

Withdrawal

XR

Extended release

y

Year

Copyright © 2011 by Oregon Health & Science University.
Bookshelf ID: NBK61821

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