FIGURE 2.6. Solid-state NMR of the molecular structure of amyloid plaque.

FIGURE 2.6Solid-state NMR of the molecular structure of amyloid plaque

Model of the minimal structural unit of amyloid fibrils based primarily on solid-state NMR data. (a) Ribbon diagram of the parallel beta-sheet structure. (b) Atomic representation of the structure with colors representing side chain type (green, hydrophobic; magenta, polar; red, negatively charged; blue positively charged).

SOURCE: Reprinted from Tycko, R. 2004. Progress towards a molecular-level structural understanding of amyloid fibrils. Curr. Opin. Struct. Biol. 14:96-103. Copyright 2004, with permission from Elsevier.

From: 2, Utilizing Chemical Imaging to Address Scientific and Technical Challenges: Case Studies

Cover of Visualizing Chemistry
Visualizing Chemistry: The Progress and Promise of Advanced Chemical Imaging.
National Research Council (US) Committee on Revealing Chemistry through Advanced Chemical Imaging.
Washington (DC): National Academies Press (US); 2006.
Copyright © 2006, National Academy of Sciences.

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