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Bookshelf ID: NBK617441PMID: 40864845
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 1263774-59-9
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the clinical use of delgocitinib during breastfeeding. Because delgocitinib cream is only applied topically to the hands, the amount in milk is likely to be low. To minimize potential infant exposure, avoid direct contact with the nipple and surrounding area immediately after applying delgocitinib cream to the hands or wrists.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Delgocitinib
CAS Registry Number
1263774-59-9
Drug Class
Breast Feeding
Milk, Human
Breast Feeding
Enzyme Inhibitors
Janus Kinase Inhibitors
JAK Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Systemic exposure and bioavailability of delgocitinib cream in adults with moderate to severe Chronic Hand Eczema.[J Eur Acad Dermatol Venereol. ...]Systemic exposure and bioavailability of delgocitinib cream in adults with moderate to severe Chronic Hand Eczema.Thaçi D, Gooderham M, Lovato P, Madsen DE, Soehoel A, Bissonnette R. J Eur Acad Dermatol Venereol. 2025 Sep; 39(9):1612-1621. Epub 2025 Jun 17.
- Review Delgocitinib 20 mg/g Cream: A Review in Chronic Hand Eczema.[Drugs. 2025]Review Delgocitinib 20 mg/g Cream: A Review in Chronic Hand Eczema.McGuigan A, Shirley M. Drugs. 2025 Sep; 85(9):1153-1162. Epub 2025 Jul 14.
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- Topical anti-inflammatory treatments for eczema: network meta-analysis.[Cochrane Database Syst Rev. 2024]Topical anti-inflammatory treatments for eczema: network meta-analysis.Lax SJ, Van Vogt E, Candy B, Steele L, Reynolds C, Stuart B, Parker R, Axon E, Roberts A, Doyle M, et al. Cochrane Database Syst Rev. 2024 Aug 6; 8(8):CD015064. Epub 2024 Aug 6.
- Delgocitinib - Drugs and Lactation Database (LactMed®)Delgocitinib - Drugs and Lactation Database (LactMed®)
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