Figure 3. Glutamate induces acute CNS injury.

Figure 3

Glutamate induces acute CNS injury. This historical schematic summarizes that seizures, hypoxia, hypoglycemia and trauma share common mechanisms of acute injury. The excitatory activity of the transmitter glutamate is linked to its toxic effects (excitotoxicity). Reprinted with permission from Choi D W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988; 1:623-634, copyright 1988 Elsevier Science.

From: Excitatory Amino Acid Neurotoxicity

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