Summary of Use during Lactation

Xanomeline is a cholinergic antipsychotic agent that is available in combination with trospium, which is a peripheral anticholinergic agent. No information is available on the clinical use of xanomeline or trospium during breastfeeding. Because trospium is a charged molecule, it is unlikely to pass well into milk. If the mother requires xanomeline, it is not a reason to discontinue breastfeeding. Until more data are available, the xanomeline-trospium combination should only be used with careful infant monitoring, particularly for gastrointestinal side effects such as nausea, vomiting diarrhea, and reflux.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Substance Name

Xanomeline

CAS Registry Number

131986-45-3

Drug Class

Breast Feeding

Lactation

Milk, Human

Antipsychotic Agents

Parasympathomimetics

Psychotropic Drugs

Muscarinic Agonists