Table 1Half-lives for some rat liver proteins

Ornithine decarboxylaseCytosol10 min
Fructose 1,6-bisphosphataseCytosol30 min
δ-Aminolevulinate synthetaseMitochondria70 min
Tyrosine aminotransferaseCytosol90 min
Tryptophan oxygenaseCytosol120 min
Hydroxymethyl CoA reductaseEndoplasmic reticulum150 min
Phosphoenol pyruvate carboxykinaseMitochondria5 h
DihydroorotaseCytosol12 h
Glucose 6-phosphate dehydrogenaseCytosol15 h
Ornithine-oxo-acid aminotransferaseMitochondria19 h
Alanine aminotransferaseMitochondria20 h
Glutamate dehydrogenaseMitochondria24 h
GlucokinaseCytosol33 h
Acetyl-CoA carboxylaseCytosol48 h
Cytochrome P450Endoplasmic reticulum50 h
Adenosine triphosphatase(F1)Mitochondria60 h
CatalasePeroxisomes60 h
Malate dehydrogenaseMitochondria62 h
Cytochrome c reductaseEndoplasmic reticulum70 h
ArginaseCytosol96 h
α-Glycerophosphate dehydrogenaseMitochondria96 h
Cytochrome b5 Mitochondria122 h
Cytochromes bc1 Mitochondria132 h
Cytochrome c oxidaseMitochondria134 h
Carbamyl phosphate synthetaseMitochondria185 h
ProteasomesCytosol/Nucleus199 h
Ornithine transcarbamylaseMitochondria209 h
β-GlucuronidaseLysosomes360 h
Lactate dehydrogenase (isozyme 5)Cytosol384 h
NAD glycohydrolaseMicrosomes432 h
Liver homogenate80 h
Nuclear homogenate115 h
Mitochondrial homogenate90 h
Microsomal homogenate45 h
Cytosolic homogenate90 h

From: Chaperone-Mediated Autophagy

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