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Leukemia

Editor: Weijie Li, MD, PHD.

Editor Information
Brisbane (AU): Exon Publications; .
ISBN-13: 978-0-6453320-7-0

Leukemia, the most common cancer in children, is a hematological malignancy caused by clonal proliferation of abnormal lymphoid or hematopoietic cells in the bone marrow and/or lymphoid system. Leukemias can be classified into many subtypes based on cell of origin, clinical, phenotypic, and genetic information. Tremendous advances have been made in the leukemia field during the last several decades. Our understanding of the biology of different types of leukemia has significantly improved through a huge amount of basic and clinical research. The application of advanced diagnostic technologies has led to the identification of not only new leukemia subtypes but also the clinical outcomes of all leukemias. One classic example is pediatric acute lymphoblast leukemia, the most common fatal disease in children, which has become a highly curable disease with a curable rate of over 80%. The book Leukemia, written by an international team has covered many of these achievements. It provides the most up-to-date information on important topics such as the new 5th Edition of the World Health Organization Classification of hematolymphoid tumors, prognostic and predictive biomarkers, minimal residual disease, pharmacogenomics, diagnostic use of flow cytometry, and gives updates on several interesting leukemia entities such as infant leukemia, hairy cell leukemia, acute myeloid leukemia with myelodysplasia-related changes, secondary acute myeloid leukemia, and myeloid/lymphoid neoplasms with PDGFRA rearrangement. This book will be of great value to a wide audience seeking information in the leukemia field either for clinical purposes or research purposes.

Contents

Weijie Li, MD, PhD, is an Associate Professor of Pathology and Laboratory Medicine at the University of Missouri-Kansas City School of Medicine and the Director of Hematopathology and Flow Cytometry at Children’s Mercy Hospital, Kansas City, USA. He is a physician board-certified in anatomic pathology, clinical pathology, and hematopathology. He has clinical expertise in the diagnosis of leukemias/lymphomas and other hematolymphoid diseases, and laboratory monitoring of the therapeutic response of these diseases, especially in acute leukemias. He is actively involved in teaching and research. He is the principal investigator or co-investigator of multiple funded research projects. His research is focused on diagnostic and prognostic markers of leukemia/lymphoma, minimal residual disease detection of acute leukemia, flow cytometry study of hematolymphoid malignancy, and the deregulation of signaling pathway in pediatric leukemia/lymphoma. He has published extensively in these areas and served as a reviewer for multiple journals in these fields.

Leukemia

ISBN: 978-0-6453320-7-0

DOI: https://doi.org/10.36255/exon-publications-leukemia

Edited by

Weijie Li, MD, PHD, Department of Pathology and Laboratory Medicine, Children’s Mercy Hospital, University of Missouri-Kansas City School of Medicine, Kansas City, USA

Published by

Exon Publications, Brisbane, Australia

Copyright© 2022 Exon Publications

Copyright of individual chapters belongs to the respective authors. The authors grant unrestricted publishing and distribution rights to the publisher. The electronic versions of the chapters are published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). https://creativecommons.org/licenses/by-nc/4.0/. Users are allowed to share and adapt the chapters for any non-commercial purposes as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source. The book in its entirety is subject to copyright by the publisher. The reproduction, modification, replication and display of the book in its entirety, in any form, by anyone, for commercial purposes are strictly prohibited without the written consent of the publisher.

Notice to the user

The views and opinions expressed in this book are believed to be accurate at the time of publication. The publisher, editors or authors cannot be held responsible or liable for any errors, omissions or consequences arising from the use of the information contained in this book. The publisher makes no warranty, implicit or explicit, with respect to the contents of this book, or its use.

First Published in October 2022

Copyright© 2022 Exon Publications.

Copyright of individual chapters belongs to the respective authors. The authors grant unrestricted publishing and distribution rights to the publisher. The electronic versions of the chapters are published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). https://creativecommons.org/licenses/by-nc/4.0/. Users are allowed to share and adapt the chapters for any non-commercial purposes as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source. The book in its entirety is subject to copyright by the publisher. The reproduction, modification, replication and display of the book in its entirety, in any form, by anyone, for commercial purposes are strictly prohibited without the written consent of the publisher.

Bookshelf ID: NBK586207PMID: 36395309DOI: 10.36255/exon-publications-leukemia

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