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Chou R, Cantor A, Dana T, et al. Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2022 Aug. (Evidence Synthesis, No. 219.)
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force [Internet].
Show detailsTable 1Statin Dosing and ACC/AHA Classification of Intensity
| Statin | Low-Intensity Dosage (LDL-C Reduction <30%) | Moderate-Intensity Dosage (LDL-C Reduction 30% to <50%) | High-Intensity Dosage (LDL-C Reduction ≥50%) |
|---|---|---|---|
| Atorvastatin | NA | 10 to 20 mg | 40 to 80 mg |
| Fluvastatin | 20 to 40 mg | 40 mg 2x/day; XL 80 mg | NA |
| Lovastatin | 20 mg | 40 to 80 mg | NA |
| Pitavastatin | NA | 1 to 4 mg | NA |
| Pravastatin | 10 to 20 mg | 40 to 80 mg | NA |
| Rosuvastatin | NA | 5 to 10 mg | 20 to 40 mg |
| Simvastatin | 10 mg | 20 to 40 mg | NA |
From ACC/AHA, 2018.199 Dosages shown are total daily dosages; exceptions are noted.
Abbreviations: ACC=American College of Cardiology; AHA=American Heart Association; LDL-C=low-density lipoprotein cholesterol; NA=not applicable.
- Table 1, Statin Dosing and ACC/AHA Classification of Intensity - Statin Use for ...Table 1, Statin Dosing and ACC/AHA Classification of Intensity - Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force
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