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Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-.

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Mother To Baby | Fact Sheets [Internet].

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Gestational Diabetes

Published online: April 2023.

This sheet is about having gestational diabetes in a pregnancy and while breastfeeding. This information should not take the place of medical care and advice from your healthcare provider.

What is gestational diabetes?

Gestational diabetes is diabetes diagnosed for the first time during pregnancy. Diabetes is a medical condition in which the body either does not make enough insulin or cannot use insulin correctly. Insulin is a hormone that is necessary for providing cells with energy to function. Insulin helps sugar (glucose) move from the bloodstream into the cells. When glucose cannot enter the cells, it builds up in the blood (hyperglycemia).

Sometimes, people have type 2 diabetes before becoming pregnant, but they do not know it. There are cases of type 2 diabetes that are not diagnosed until later in pregnancy, so it is called gestational diabetes but it was actually there all along. Because type 2 diabetes is becoming more common, it has been suggested that all people who want to become pregnant talk with their healthcare provider about being checked for diabetes before becoming pregnant.

Well-controlled glucose levels are when your levels are in the range that acceptable for you. Uncontrolled or poorly-controlled glucose levels means your blood sugar levels are too high, even if you're treating your condition. What is considered well-controlled, poorly-controlled and uncontrolled can vary from person to person. In general, the goals for glycemic control for people with gestational diabetes are:

  • Before a meal (preprandial) ≤95 mg/dL (5.3 mmol/L)
  • 1-hour post-meal ≤140 mg/dL (7.8 mmol/L)
  • 2-hours post-meal ≤120 mg/dL (6.7 mmol/L)

However, because every person and every pregnancy are different, it is important to work with your healthcare team to determine what your glucose goals are and how to meet them during pregnancy.

Does having gestational diabetes increase the chance of miscarriage?

Miscarriage can occur in any pregnancy. When glucose levels are not well-controlled during pregnancy, there is an increased chance for miscarriage and stillbirth.

Does having gestational diabetes increase the chance of birth defects?

Every pregnancy starts out with a 3-5% chance of having a birth defect. This is called the background risk. Gestational diabetes has not been associated with birth defects in most studies, but there are some studies that suggest an increased chance for certain birth defects. It is possible that these birth defects are due to obesity, which can also cause gestational diabetes.

Would having gestational diabetes increase the chance of other pregnancy related problems?

When glucose levels are not well-controlled during pregnancy, there is a higher chance of pre-eclampsia (a pregnancy related disorder that can lead to dangerously high blood pressure), too much amniotic fluid around the baby (polyhydramnios), and delivery before 37 weeks of pregnancy (preterm delivery). A person with diabetes during pregnancy also has an increased chance of having a baby who has trouble breathing, low blood sugar (hypoglycemia) and jaundice (yellowing of the skin and the whites of the eyes) at birth. In addition, having gestational diabetes increases the chance of having large babies (called macrosomia), some weighing over 10 pounds.

Can having gestational diabetes in pregnancy cause long-term complications for the baby?

Infants of parents with gestational diabetes have an increased chance of developing diabetes later in life. This is thought to be caused by both genetics and diabetes management (glucose control) during pregnancy. Some studies suggest that poorly-controlled diabetes during pregnancy could affect development of the central nervous system (CNS), which can increase the chance of problems with learning, behavior, and development. However, data from these studies are limited.

How are people screened for gestational diabetes?

Most people who are pregnant are screened for gestational diabetes around 24 to 28 weeks of pregnancy by drinking a glucose solution and having their blood glucose level tested one hour later. If this test is abnormal, a longer test may be done to verify the diagnosis of gestational diabetes.

People who have had gestational diabetes in a previous pregnancy have a greater chance of having it again in later pregnancies. If you have had gestational diabetes in a previous pregnancy, your healthcare provider may want you to take the glucose screening test earlier in pregnancy. Talk to your healthcare provider to go over the screening or testing options that are right for you.

How is gestational diabetes treated?

In most cases of gestational diabetes, blood glucose levels can be controlled with dietary changes and exercise. In some cases, medications may be needed. You can discuss questions about a specific medication with your healthcare provider or by contacting a MotherToBaby specialist.

What kinds of tests are recommended during pregnancy for people with diabetes?

Your healthcare providers will follow the health of you and your developing baby closely during the pregnancy. They will talk with you about the correct screening tests for your pregnancy.

Does gestational diabetes go away after I deliver my baby?

For most people, gestational diabetes goes away soon after delivery. If it does not go away, it is called type 2 diabetes. About 50% (1 in 2) of all people who had gestational diabetes develop type 2 diabetes later in life. It is suggested that people who had gestational diabetes get tested for diabetes 6 to 12 weeks after their baby is born, and then every 1 to 3 years. It is important for a person who has had gestational diabetes to continue to exercise and eat a healthy diet after pregnancy to prevent or delay getting type 2 diabetes.

Does having gestational diabetes in pregnancy affect future behavior or learning for the child?

Studies have not been done to see if gestational diabetes can cause behavior or learning issues for the child.

Breastfeeding while I have gestational diabetes:

There are many health benefits of breastfeeding and people who have gestational diabetes should not be discouraged from breastfeeding. People with diabetes should make sure their glucose levels are well-controlled when breastfeeding. Some research has found that high maternal glucose can overflow into the breast milk as sugar. This could cause hypoglycemia and increased food-seeking behavior in the infant. Be sure to talk to your healthcare provider about all of your breastfeeding questions.

Selected References:

  • Adane AA, et al. 2016. Diabetes in pregnancy and childhood cognitive development: a systematic review. Pediatrics, 137(5):e20154234. [PubMed: 27244820]
  • American Diabetes Association. 2015. Management of diabetes in pregnancy. Diabetes Care, 38 Suppl:S77–9. [PubMed: 25537713]
  • Bhattacharyya A, et al. 2001. Insulin lispro and regular insulin in pregnancy. QJM. 94(5):255-260. [PubMed: 11353099]
  • Bytoft B, et al. 2016. Long-term cognitive implications of intrauterine hyperglycemia in adolescent offspring of women with type 1 diabetes (the EPICOM Study). Diabetes Care, 39:1356-1363. [PubMed: 27271191]
  • Chehab RF, et al. 2022. Glycemic control trajectories and risk of perinatal complications among individuals with gestational diabetes. JAMA Netw Open, 5(9):e2233955. [PMC free article: PMC9523493] [PubMed: 36173631]
  • Coetzee EJ and Levitt NS. 2000. Maternal diabetes and neonatal outcome. Seminars in Neonatology. 5(3):221-229. [PubMed: 10956447]
  • Feleke BE, et al. 2022. Maternal and newborn effects of gestational diabetes mellitus: A prospective cohort study. Prim Care Diabetes, 16(1):89-95. [PubMed: 34561156]
  • Landon MB. 2000. Obstetric management of pregnancies complicated by diabetes mellitus. Clinical Obstetrics and Gynecology, 43(1):65-74. [PubMed: 10694989]
  • Langer O, et al. 2000. A comparison of glyburide and insulin in women with gestational diabetes mellitus. New England Journal of Medicine, 343(16):1134-1138. [PubMed: 11036118]
  • National Institute of Child Health and Human Development. 2011. Managing Gestational Diabetes: A Patient’s Guide to a Healthy Pregnancy. Available at: https://www​.nichd.nih​.gov/publications/product/211 . [Accessed February 2023]
  • Ornoy A. Growth and neurodevelopmental outcome of children born to mothers with pregestational and gestational diabetes. 2005. Pediatr Endocrinol Rev, ;3(2):104–113. [PubMed: 16361984]
  • Papazoglou AS, et al. 2022. Maternal diabetes mellitus and its impact on the risk of delivering a child with congenital heart disease: a systematic review and meta-analysis. J Matern Fetal Neonata. Med, 35(25):7685-7694. [PubMed: 34353219]
  • Pectasides M and Kalva S. 2011. Diabetes revealed: multisystem danger. American Journal of Roentgenology, 196(2): 274-286. [PubMed: 21257877]
  • Preda A, et al. 2021. Analysis of maternal and neonatal complications in a group of patients with gestational diabetes mellitus. Medicina, 57(11):1170. [PMC free article: PMC8619358] [PubMed: 34833388]
  • Rizzo TA, et al. 1995. Prenatal and perinatal influences on long-term psychomotor development in offspring of diabetic mothers. Am J Obstet Gynecol, 173(6):1753-1758. [PubMed: 8610757]
  • Rosenn BM and Miodovnik M. 2000. Medical complications of diabetes mellitus in pregnancy. Clinical Obstetrics and Gynecology, 43(1):17-31. [PubMed: 10694985]
  • Sells CJ, et al. 1994. Long-term developmental follow-up of infants of diabetic mothers. J Pediatr, 125(1):S9-17. [PubMed: 8021756]
  • Serlin D and Last R. 2009. Diagnosis and management of gestational diabetes mellitus. American Family Physician, 80(1): 57-62. [PubMed: 19621846]

OTIS/MotherToBaby encourages inclusive and person-centered language. While our name still contains a reference to mothers, we are updating our resources with more inclusive terms. Use of the term mother or maternal refers to a person who is pregnant. Use of the term father or paternal refers to a person who contributes sperm.

Copyright by OTIS, April 2023.

This work is available under the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported license (CC BY-NC-ND 3.0)

Bookshelf ID: NBK582729PMID: 35952000

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