FIGURE 32.4.. Schematic representations of calreticulin (CRT) and calnexin (CNX) showing the lectin domain, the P domain (containing the proline repeats), and the calcium-binding domain (A,B).

FIGURE 32.4.

Schematic representations of calreticulin (CRT) and calnexin (CNX) showing the lectin domain, the P domain (containing the proline repeats), and the calcium-binding domain (A,B). Structure of CNX based on crystallographic data (C). (Adapted, with permission of Elsevier, from Schrag JD, et al. 2001. Mol. Cell 8: 633–644.) Structures of the lectin domains of ERGIC-53 and VIP36 based on crystallographic data shown in cartoon and surface representation with the ligands indicated in stick representation (D,E).

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From: Chapter 32, L-Type Lectins

Cover of Essentials of Glycobiology
Essentials of Glycobiology [Internet]. 4th edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.
Copyright © 2022 The Consortium of Glycobiology Editors, La Jolla, California; published by Cold Spring Harbor Laboratory Press; doi:10.1101/glycobiology.4e.32. All rights reserved.

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