Agents Included in LiverTox by Drug Class

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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

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Agents Included in LiverTox by Drug Class

Last Update: October 9, 2024.

Drugs by Class:

ACE Inhibitors
- See Angiotensin-Converting Enzyme Inhibitors
Acetaminophen
Agents of Abuse
- Amphetamines, Cocaine, Ecstasy (see Amphetamines), Ketamine, Khat, Phencyclidine
Alkylating Agents
- Altretamine,Bendamustine, Busulfan, Carmustine, Chlorambucil, Cyclophosphamide, Dacarbazine, Ifosfamide, Lomustine, Lurbinectedin, Mechlorethamine, Melphalan, Procarbazine, Streptozocin, Temozolomide, Thiotepa, Trabectedin
- Platinum Coordination Complexes
  - Carboplatin, Cisplatin, Oxaliplatin
Alpha-1 Adrenergic Receptor Antagonists
- Doxazosin, Prazosin, Terazosin
Alzheimer Disease Agents
- Aducanumab, Donepezil, Edaravone, Galantamine, Lecanemab, Memantine, Riluzole, Rivastigmine, Tacrine
Aminoglycosides
- Amikacin, Gentamicin, Neomycin, Plazomicin, Streptomycin, Tobramycin
Amoxicillin-Clavulanate
Anabolic Steroids
- Danazol, Fluoxymesterone, Methandienone, Methenolone, Methyltestosterone, Nandrolone, Norethandrolone, Oxandrolone, Oxymetholone, Stanozolol, Testosterone
Analgesics
- See Nonsteroidal Antiinflammatory Drugs (NSAIDs)
- See Opioids, Opioid Antagonists
Androgenic Steroids
- See Anabolic Steroids
Anesthetics, General
- Barbiturates
  - Amobarbital, Methohexital, Thiopental
- Halogenated
  - Desflurane, Enflurane, Halothane, Isoflurane, Sevoflurane
- Miscellaneous
  - Ketamine, Nitrous Oxide, Propofol
Anesthetics, Local
- Amides
  - Articaine, Bupivacaine, Lidocaine, Mepivacaine, Prilocaine, Ropivacaine
Angiotensin-Converting Enzyme Inhibitors
- Benazepril, Captopril, Enalapril, Fosinopril, Lisinopril, Moexipril, Perindopril, Quinapril, Ramipril, Trandolapril
Angiotensin II Receptor Antagonists
- Azilsartan, Candesartan, Eprosartan, Irbesartan, Losartan, Olmesartan, Telmisartan, Valsartan
Anthelmintic Agents
- Albendazole, Ivermectin, Mebendazole, Nitazoxanide, Pentamidine, Praziquantel, Pyrantel, Thiabendazole, Triclabendazole
Anthrax Antitoxins
- See Antiinfective Agents, Antitoxins
Antiandrogens
- Abiraterone, Bicalutamide, Cyproterone, Enzalutamide, Flutamide, Nilutamide
Antiangina Agents
- Organic Nitrates
  - Isosorbide Dinitrate, Isosorbide Mononitrate, Nitroglycerin
- Ranolazine
Antianxiety Agents
- See Benzodiazepines
- See Sedatives and Hypnotics
Antiarrhythmic Agents
- Amiodarone, Disopyramide, Dofetilide, Dronedarone, Flecainide, Ivabradine, Mexiletine, Procainamide, Propafenone, Quinidine
Antiasthmatic Agents
- Beta-2 Adrenergic Agonists
  - Albuterol, Bitolterol, Formoterol, Metaproterenol, Pirbuterol, Salbutamol, Salmeterol, Terbutaline
- Leukotriene Receptor Antagonists
  - Montelukast, Zafirlukast
- Monoclonal Antibodies
  - Benralizumab, Dupilumab, Mepolizumab, Omalizumab, Reslizumab, Tezepelumab
- Xanthine Derivatives
  - Theophylline
- Zileuton
Anticholinergic Agents
- Aclidinium, Atropine, Homatropine, Darifenacin, Dicyclomine, Fesoterodine, Flavoxate, Glycopyrrolate, Hyoscyamine, Ipratropium, Mepenzolate, Methscopolamine, Oxybutynin, Propantheline, Revefenacin, Scopolamine, Solifenacin, Tiotropium, Tolterodine, Trospium
Anticoagulants
- See Antithrombotic Agents
Anticonvulsants
- Brivaracetam, Cannabidiol, Carbamazepine, Cenobamate, Clobazam, Clonazepam, Clorazepate, Diazepam, Eslicarbazepine, Ethosuximide, Ezogabine, Felbamate, Fosphenytoin, Gabapentin, Gabapentin Enacarbil, Lacosamide, Lamotrigine, Levetiracetam, Methsuximide, Oxcarbazepine, Perampanel, Phenobarbital, Phenytoin, Pregabalin, Primidone, Rufinamide, Stiripentol, Tiagabine, Topiramate, Valproate, Vigabatrin, Zonisamide
Antidepressant Agents
- MAO Inhibitors
  - Isocarboxazid, Phenelzine, Tranylcypromine
- SNRIs
  - Duloxetine, Levomilnacipran, Venlafaxine
- SSRIs
  - Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Vilazodone, Vortioxetine
- Tricyclics
  - Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin, Imipramine, Nortriptyline, Protriptyline, Trimipramine
- Miscellaneous
  - Brexanolone, Bupropion, Esketamine, Flibanserin, Mirtazapine, Nefazodone, Trazodone
Antidiabetic Agents
- Alpha-Glucosidase Inhibitors
  - Acarbose, Miglitol
- Incretin-Based Drugs
  - Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
    - Alogliptin, Linagliptin, Saxagliptin, Sitagliptin
  - Glucagon-Like Peptide-1 (GLP-1) Analogues
    - Albiglutide, Dulaglutide, Exenatide, Liraglutide, Lixisenatide, Semaglutide, Tirzepatide
- Insulin
- Metformin
- Metiglinide Analogues
  - Nateglinide, Repaglinide
- Pramlintide
- Sodium Glucose Cotransporter-2 (SGLT2) Inhibitors
  - Bexagliflozin, Canagliflozin, Dapagliflozin, Empagliflozin, Ertugliflozin
- Sulfonylureas
  - First Generation Sulfonylureas
    - Acetohexamide, Chlorpropamide, Tolazamide, Tolbutamide
  - Second Generation Sulfonylureas
    - Gliclazide, Glimepiride, Glipizide, Glyburide (Glibenclamide)
- Thiazolidinediones
  - Pioglitazone, Rosiglitazone, Troglitazone
- Miscellaneous
  - Teplizumab
Antidotes, Toxicological Emergency
- Acetylcysteine
- See also Chelating Agents
- See also Opioids, Opioid Antagonists
Antiemetic Agents
- Anticholinergic Agents
  - Hyoscyamine, Methscopolamine, Scopolamine
- Antihistamines
  - Cyclizine, Dimenhydrinate, Hydroxyzine, Meclizine, Promethazine
- Cannabinoid Receptor Agonists
  - Dronabinol, Nabilone, Tetrahydrocannabinol
- Phenothiazines [See Antipsychotic Agents]
  - Chlorpromazine, Prochlorperazine
- Serotonin 5-HT3 Receptor Antagonists
  - Alosetron, Dolasetron, Granisetron, Ondansetron, Palonosetron
- Substance P/Neurokinin 1 Receptor Antagonists
  - Aprepitant, Fosaprepitant, Fosnetupitant, Rolapitant
- Miscellaneous
  - Amisulpride, Dexamethasone, Metoclopramide, Trimethobenzamide
Antifungal Agents
- Amphotericin B, Anidulafungin, Caspofungin, Clotrimazole, Echinocandins, Fluconazole, Flucytosine, Griseofulvin, Isavuconazonium, Itraconazole, Ketoconazole, Micafungin, Nystatin, Pentamidine, Posaconazole, Terbinafine, Voriconazole
Antigout Agents
- Allopurinol, Benzbromarone, Colchicine, Febuxostat, Lesinurad, Pegloticase, Probenecid, Rasburicase
Antihistamines
- First Generation
  - Brompheniramine, Carbinoxamine, Chlorcyclizine, Chlorpheniramine, Clemastine, Cyclizine, Cyproheptadine, Dexbrompheniramine, Dexchlorpheniramine, Dimenhydrinate, Diphenhydramine, Doxylamine, Hydroxyzine, Meclizine, Phenyltoloxamine, Promethazine, Triprolidine
- Second Generation
  - Acrivastine, Cetirizine, Fexofenadine, Levocetirizine, Loratadine, Desloratadine
Antihypertensive Agents
- Aliskiren, Clonidine, Guanfacine, Hydralazine, Methyldopa, Minoxidil, Sodium Nitroprusside, Reserpine
- Alpha-1 Adrenergic Receptor Antagonists
  - Doxazosin, Prazosin, Terazosin
- Sacubitril-Valsartan [Heart Failure Agent]
- See also Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Antagonists, Beta-Adrenergic Receptor Antagonists, Calcium Channel Blockers, Diuretics
Antiinfective Agents
- Antibacterial Agents, Classes
  - Aminoglycosides, Carbapenems, Cephalosporins, Fluoroquinolones, Glycopeptides, Macrolide Antibiotics, Penicillins, Sulfonamides, Tetracyclines
- Antibacterial Agents, Miscellaneous
  - Aztreonam, Benznidazole, Chloramphenicol, Clindamycin, Daptomycin, Fosfomycin, Lefamulin, Linezolid, Methenamine, Metronidazole, Nitrofurantoin, Quinupristin-Dalfopristin, Secnidazole, Tedizolid, Tinidazole, Vancomycin
- Antifungal Agents
- Antihelmintic Agents
- Antimalarial Agents
- Antitoxins
  - Bezlotoxumab, Obiltoxaximab, Raxibacumab
- Antituberculosis Agents
- Antiviral Agents
- Leishmaniasis Agents
  - Miltefosine
- Leprosy Agents
  - Clofazimine, Dapsone, Rifampin
Antilipemic Agents
- Bile Acid Resins/Sequestrants
  - Cholestyramine, Colesevelam, Colestipol
- Fibrates
  - Clofibrate, Fenofibrate, Gemfibrozil
- Monoclonal Antibodies
  - Anti-PCSK9
    - Alirocumab, Evolocumab
  - Anti-ANGPTL3
    - Evinacumab
- Niacin (Nicotinic Acid)
- Omega-3 Fatty Acids,
  - Icosapent Ethyl, Omega-3 Acid Ethyl Esters, Omega-3 Carboxylic Acids
- Statins
  - Atorvastatin, Fluvastatin, Lovastatin, Pitavastatin, Pravastatin, Rosuvastatin, Simvastatin
- Miscellaneous
  - Bempedoic Acid, Ezetimibe, Lomitapide, Mipomersen, Resmetirom
Antimalarial Agents
- Amodiaquine, Artemisinin, Atovaquone, Chloroquine, Mefloquine, Mepacrine, Primaquine, Proguanil, Quinine, Tafenoquine
Anti-Migraine
- See Migraine Headache Agents
Antineoplastic Agents
- Alkylating Agents
  - Altretamine, Bendamustine, Busulfan, Carmustine, Chlorambucil, Cyclophosphamide, Dacarbazine, Ifosfamide, Lomustine, Lurbinectedin, Mechlorethamine, Melphalan, Procarbazine, Streptozocin, Temozolomide, Thiotepa, Trabectedin
  - Platinum Coordination Complexes
    - Carboplatin, Cisplatin, Oxaliplatin
- Antibiotics, Cytotoxic
  - Bleomycin, Dactinomycin, Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitomycin, Mitoxantrone, Plicamycin [Mithramycin], Valrubicin
- Antimetabolites
  - Antifolates
    - Methotrexate, Pemetrexed, Pralatrexate, Trimetrexate
  - Purine Analogues
    - Azathioprine, Cladribine, Clofarabine, Fludarabine, Mercaptopurine, Nelarabine, Pentostatin, Thioguanine
  - Pyrimidine Analogues
    - Azacitidine, Capecitabine, Cytarabine, Decitabine, Floxuridine, Fluorouracil, Gemcitabine, Trifluridine/Tipracil
- Biologic Response Modifiers
  - Aldesleukin (IL-2), Denileukin Diftitox, Interferon gamma
- Histone Deacetylase Inhibitors
  - Belinostat, Panobinostat, Romidepsin, Vorinostat
- Hormonal Agents
  - Antiandrogens
    - Abiraterone, Apalutamide, Bicalutamide, Cyproterone, Enzalutamide, Flutamide, Nilutamide
  - Antiestrogens (including Aromatase Inhibitors)
    - Anastrozole, Exemestane, Fulvestrant, Letrozole
    - Selective Estrogen Receptor Modulators
      - Raloxifene, Tamoxifen, Toremifene
  - Gonadotropin Releasing Hormone Analogues
    - Degarelix, Goserelin, Histrelin, Leuprolide, Relugolix, Triptorelin
  - Peptide Hormones
    - Lanreotide, Octreotide, Pasireotide
- Monoclonal Antibodies
  - Alemtuzumab, Atezolizumab, Avelumab, Belantamab, Bevacizumab, Blinatumomab, Brentuximab, Cemiplimab, Cetuximab, Daratumumab, Dinutuximab, Dostarlimab, Durvalumab, Elotuzumab, Enfortumab, Gemtuzumab, Inotuzumab Ozogamicin, Ipilimumab, Margetuximab, Mogamulizumab, Moxetumomab Pasudotox, Naxitamab, Necitumumab, Nivolumab, Ofatumumab, Olaratumab, Panitumumab, Pembrolizumab, Pertuzumab, Polatuzumab Vedotin, Ramucirumab, Rituximab, Sacituzumab Govitecan, Tafasitamab, Teclistamab, Tisotumab Vedotin, Tositumomab, Trastuzumab, Trastuzumab Deruxtecam, Trastuzumab Emtansine, Tremelimumab
- Protein Kinase Inhibitors
  - Abemaciclib, Acalabrutinib, Adagrasib, Afatinib, Alectinib, Alpelisib, Asciminib, Avapritinib, Axitinib, Binimetinib, Bortezomib, Bosutinib, Brigatinib, Cabozantinib, Capmatinib, Carfilzomib, Ceritinib, Cobimetinib, Copanlisib, Crizotinib, Dabrafenib, Dacomitinib, Dasatinib, Duvelisib, Enasidenib, Encorafenib, Entrectinib, Erdafitinib, Erlotinib, Fedratinib, Futibatinib, Gefitinib, Gilteritinib, Glasdegib, Ibrutinib, Idelalisib, Imatinib, Infigratinib, Ivosidenib, Ixazomib, Lapatinib, Larotrectinib, Lenvatinib, Lorlatinib, Midostaurin, Mobocertinib, Momelotinib, Neratinib, Nilotinib, Niraparib, Olaparib, Olutasidenib, Osimertinib, Pacritinib, Palbociclib, Pazopanib, Pemigatinib, Pexidartinib, Pirtobrutinib, Ponatinib, Pralsetinib, Quizartinib, Regorafenib, Ribociclib, Ripretinib, Rucaparib, Ruxolitinib, Selpercatinib, Selumetinib, Sonidegib, Sorafenib, Sotorasib, Sunitinib, Talazoparib, Tepotinib, Tivozanib, Trametinib, Trilaciblib, Tucatinib, Umbralisib, Vandetanib, Vemurafenib, Vismodegib, Zanubrutinib
- Taxanes
  - Cabazitaxel, Docetaxel, Paclitaxel
- Topoisomerase Inhibitors
  - Etoposide, Irinotecan, Teniposide, Topotecan
  - Tyrosine Kinase Receptor Inhibitors
- Vinca Alkaloids
  - Vinblastine, Vincristine, Vinorelbine
- Miscellaneous
  - Asparaginase (Pegaspargase), Belzutifan, Bexarotene, Cedazuridine, Eribulin, Everolimus, Hydroxyurea, Ixabepilone, Lenalidomide, Mitotane, Omacetaxine, Pomalidomide, Selinexor, Tagraxofusp, Tazemetostat, Tebentafusp, Telotristat, Temsirolimus, Thalidomide, Venetoclax
Antiparkinson Agents
- See Parkinson Disease Agents
Antiplatelet Agents
- See Antithrombotic Agents
Antipsychotic Agents
- First Generation
  - Phenothiazines
    - Chlorpromazine, Fluphenazine, Perphenazine, Prochlorperazine, Thioridazine, Trifluoperazine
  - Other
    - Haloperidol, Lithium, Loxapine, Molindone, Pimozide
- Second Generation (Atypicals)
  - Aripiprazole, Asenapine, Brexpiprazole, Cariprazine, Clozapine, Iloperidone, Lumateperone, Lurasidone, Olanzapine, Paliperidone, Pimavanserin, Quetiapine, Risperidone, Ziprasidone
Antirheumatic Agents
- Gold Preparations
  - Auranofin, Gold Salts, Gold Sodium Thiomalate
- Interleukin Receptor Antagonists
  - Anakinira, Canakinumab, Rilonacept, Sarilumab, Tocilizumab
- Major Immunosuppressive Agents
  - Cyclosporine, Mycophenylate, Sirolimus, Tacrolimus
- Monoclonal Antibodies
  - Adalimumab, Canakinumab, Certolizumab, Golimumab, Infliximab, Rituximab, Sarilumab, Tocilizumab, Ustekinumab
- Thiopurines
  - Azathioprine, Mercaptopurine, Thioguanine
- Tumor Necrosis Factor Antagonists
  - Adalimumab, Certolizumab, Etanercept, Golimumab, Infliximab
- Tyrosine (Janus) Kinase Inhibitors
  - Baricitinib, Tofacitinib, Upadacitinib
- Miscellaneous
  - Abatacept, Flavocoxid, Hydroxychloroquine, Leflunomide, Methotrexate, Penicillamine
Antithrombotic Agents
- Anticoagulants
- Antiplatelet Agents
  - Aspirin, Cangrelor, Clopidogrel, Dipyridamole, Prasugrel, Ticagrelor, Ticlopidine, Vorapaxar
- Miscellaneous
  - Anagrelide, Defibrotide, Drotrecogin alfa
Antithyroid Agents
- See Thyroid and Antithyroid Agents
Antitoxins
- Bezlotoxumab, Obiltoxaximab, Raxibacumab
Antituberculosis Agents
- Bedaquiline, Capreomycin, Cycloserine, Ethambutol, Ethionamide, Isoniazid, Pretomanid, Pyrazinamide, Rifabutin, Rifampin, Rifapentine, Streptomycin
Antiulcer Agents
- Proton Pump Inhibitors
  - Dexlansoprazole, Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole
- Selective Histamine Type 2 Receptor Antagonists/Blockers
  - Cimetidine, Famotidine, Nizatidine, Ranitidine
Antiviral Agents
- Attachment Inhibitors (HIV)
  - Fostemsavir
- Fusion Inhibitors (HIV)
  - Enfuvirtide, Maraviroc
- Integrase Inhibitors (HIV)
  - Bictegravir, Cabotegravir, Dolutegravir, Elvitegravir, Raltegravir
- Monoclonal Antibodies
  - Ibalizumab
- Neuraminidase and Endonuclease Inhibitors (Influenza)
  - Baloxavir, Oseltamivir, Peramivir, Zanamivir
- Nonnucleoside Reverse Transcriptase Inhibitors
  - Delavirdine, Doravirine, Efavirenz, Etravirine, Nevirapine, Rilpivirine
- Nucleoside Analogues
  - Abacavir, Acyclovir, Adefovir, Brincidofovir, Cidofovir, Didanosine, Emtricitabine, Entecavir, Famciclovir, Ganciclovir/Valganciclovir, Lamivudine, Remdesivir, Sofosbuvir, Stavudine, Telbivudine, Tenofovir, Valacyclovir, Zidovudine
- Protease Inhibitors (Hepatitis C/HCV)
  - Asunaprevir, Boceprevir, Glecaprevir, Grazoprevir, Paritaprevir, Simeprevir, Telaprevir
  - See also Hepatitis C (HCV) Drugs
- Protease Inhibitors (HIV)
  - Amprenavir, Atazanavir, Darunavir, Fosamprenavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir, Saquinavir, Tipranavir
- Miscellaneous
  - Acyclovir, Alpha Interferon, Amantadine, Cidofovir, Famciclovir, Foscarnet, Ganciclovir, Letermovir, Maribavir, Peginterferon, Ribavirin, Rimantadine, Tecovirimat, Valacyclovir, Valganciclovir
Attention Deficit/Hyperactivity Disorder (ADHD) Agents
- Stimulants
  - Amphetamines, Methylphenidate
- Nonstimulants
  - Atomoxetine, Clonidine, Guanfacine, Viloxazine
Aztreonam
Benign Prostatic Hypertrophy Agents
- Alpha-1 Adrenergic Receptor Antagonists
  - Alfuzosin, Silodosin, Tamsulosin
- 5-Alpha Reductase Inhibitors
  - Dutasteride, Finasteride
Benzodiazepines
- Alprazolam, Chlordiazepoxide, Clobazam, Clonazepam, Clorazepate, Diazepam (Intravenous), Diazepam (Oral), Estazolam, Flurazepam, Lorazepam, Midazolam, Oxazepam, Quazepam, Remimazolam, Temazepam, Triazolam
Beta-Adrenergic Receptor Antagonists
- Acebutolol, Atenolol, Betaxolol, Bisoprolol, Carvedilol, Esmolol, Labetalol, Metoprolol, Nadolol, Nebivolol, Penbutolol, Pindolol, Propranolol, Sotalol, Timolol
Bisphosphonates
- Alendronate, Etidronate, Ibandronate, Pamidronate, Risedronate, Zoledronic Acid
Caffeine
- See Energy Drinks
Calcium Channel Blockers
- Amlodipine, Diltiazem, Felodipine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Nisoldipine, Verapamil
Carbapenems
- Doripenem, Ertapenem, Imipenem-Cilastatin, Meropenem
Cardiac Glycosides
- Digitalis, Digoxin
Central Nervous System (CNS) Stimulants
- Amphetamines, Atomoxetine, Cocaine, Methylphenidate, Modafinil and Armodafinil (Isomers), Oxybate, Pitolisant, Solriamfetol
Cephalosporins
- Cefaclor, Cefadroxil, Cefazolin, Cefdinir, Cefditoren, Cefepime, Cefixime, Cefoperazone, Cefotaxime, Cefoxitin, Cefpodoxime, Cefprozil, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Cefuroxime, Cephalexin, Cephradine
Chelating Agents
- Arsenic Chelators
  - Dimercaprol
- Copper Chelators (for Wilson Disease)
  - Dimercaprol, Penicillamine, Trientine, Zinc
- Iron Chelators
  - Deferasirox, Deferiprone, Deferoxamine
- Lead Chelators
  - Dimercaprol, [EDTA; not in LiverTox], Succimer
- Mercury Chelators
  - Dimercaprol
Cholesterol Lowering Agents
- See Antilipemic Agents
Chronic Obstructive Pulmonary Disease Agents
- See Pulmonary Disease Agents
Corticosteroids
- Budesonide, Cortisol, Cortisone, Dexamethasone, Hydrocortisone, Methylprednisolone, Prednisolone, Prednisone, Triamcinolone
COVID-19 Drugs
- Azithromycin, Baricitinib, Chloroquine, Corticosteroids, Dexamethasone, Favipiravir, Fluvoxamine, Hydroxychloroquine, Ivermectin, Molnupiravir, Paxlovid, Remdesivir, Ruxolitinib, Sarilumab, Tocilizumab, Tofacitinib
COVID-19 Monoclonal Antibodies [Monoclonal Antibodies to SARS-CoV-2]
- Bamlanivimab, Casirivimab, Etesevimab, Imdevimab, Sotrovimab
COVID-19 Vaccines
Dermatologic Agents
- Atopic Dermatitis
  - Abrocitinib, Dupilumab, Tralokinumab
- Psoriasis Agents
  - Acitretin, Alefacept, Apremilast, Cyclosporine, Methotrexate, Psoralen (Methoxsalen)
  - Monoclonal Antibodies
    - IL-17A Antagonists
      - Brodalumab, Ixekizumab, Secukinumab
    - Tumor Necrosis Factor Antagonists
      - Adalimumab, Certolizumab, Etanercept, Golimumab, Infliximab
    - Other
      - Deucravacitinib, Efalizumab, Guselkumab, Risankizumab, Tildrakizumab, Ustekinumab
Disulfiram
Diuretics
- Carbonic Anhydrase Inhibitors
  - Acetazolamide, Methazolamide
- Loop Diuretics
  - Bumetanide, Ethacrynic Acid, Furosemide, Torsemide
- Potassium-Sparing Diuretics
  - Amiloride, Eplerenone, Spironolactone, Triamterene
- Thiazide Diuretics
  - Bendroflumethiazide, Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Polythiazide
- Vasopressin Antagonists
  - Tolvaptan Triamterene
- Miscellaneous
  - Finerenone
Drugs of Abuse
- See Agents of Abuse
Endocrine Disease Agents
- Osilodrostat
Energy Drinks
Estrogens and Oral Contraceptives
- See Obstetrical and Gynecological Agents
Fibromyalgia Agents
- Milnacipran
Fluoroquinolones
- Ciprofloxacin, Delafloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin, Norfloxacin, Ofloxacin
Gastrointestinal Agents
- Antidiarrheals
  - Absorbents and Protectants
    - Bismuth, Kaolin, Pectin
  - Antimotility Agents
    - Difenoxin, Diphenoxylate, Loperamide
  - Bile Acid Resins/Sequestrants [See Antilipemic Agents]
    - Cholestyramine, Colesevelam, Colestipol
  - Bulk-Forming Agents
    - Methylcellulose
  - Travelers' Diarrhea
    - Rifamycin, Rifaximin
  - Miscellaneous
    - Crofelemer, Octreotide, Somatostatin
- Antiemetic Agents
  - Anticholinergic Agents
    - Hyoscyamine, Methscopolamine, Scopolamine
  - Antihistamines
    - Cyclizine, Dimenhydrinate, Hydroxyzine, Meclizine, Promethazine
  - Cannabinoid Receptor Agonists
    - Dronabinol, Nabilone, Tetrahydrocannabinol
  - Phenothiazines [See Antipsychotic Agents]
    - Chlorpromazine, Prochlorperazine
  - Serotonin 5-HT3 Receptor Antagonists
    - Alosetron, Dolasetron, Granisetron, Ondansetron, Palonosetron
  - Substance P/Neurokinin 1 Receptor Antagonists
    - Aprepitant, Fosaprepitant, Fosnetupitant, Rolapitant
  - Miscellaneous
    - Amisulpride, Dexamethasone, Metoclopramide, Trimethobenzamide
- Acid-Peptic Disease Agents/Antiulcer Agents
  - Proton Pump Inhibitors
    - Dexlansoprazole, Esomeprazole, Lansoprazole, Omeprazole, Pantoprazole, Rabeprazole
  - Selective Histamine Type 2 Receptor Antagonists/Blockers
    - Cimetidine, Famotidine, Nizatidine, Ranitidine
- Bile Acids
  - Chenodiol (Chenodeoxycholic Acid), Cholic Acid, Obeticholic Acid, Ursodiol (Ursodeoxycholic Acid)
- Cathartics and Laxatives
  - Anthraquinones
    - Cascara Sagrada, Senna
  - Bulk-Forming
    - Fiber, Bran, Methylcellulose
  - Opioid Antagonists
    - Naloxego, Naldemedine
  - Saline
    - Magnesium Sulfate
  - Stimulant
    - Bisacodyl, Castor Oil
  - Stool Softeners
    - Docusate, Lactulose
  - Miscellaneous
    - Plecanatide, Prucalopride
- Inflammatory Bowel Disease Agents
  - 5-Aminosalicyclic Acid (5-ASA) Derivatives
    - Balsalazide, Mesalamine, Olsalazine, Sulfasalazine
  - Immunosuppressive Agents
    - Azathioprine, Mercaptopurine, Methotrexate
  - Tumor Necrosis Factor Antagonists
    - Adalimumab, Certolizumab, Golimumab, Infliximab
  - Miscellaneous
    - Metronidazole, Natalizumab, Vedolizumab
- Irritable Bowel Syndrome Agents
  - Antimuscarinics/Antispasmodics [See Anticholinergic Agents]
    - Dicyclomine, Glycopyrrolate, Hyoscyamine, Methscopolamine
  - Prokinetic Agents [See Serotonin 5-HT4 Receptor Agonists]
    - Alosetron, Cisapride, Domperidone, Linaclotide, Lubiprostone, Metoclopramide, Plecanatide, Prucalopride, Tegaserod
  - Other
    - Eluxadoline, Tenapanor
Genetic Disorder Agents
- Activated PI3K-delta Syndrome
  - Leniolisib
- siRNA and Antisense Agents
  - Acute Hepatic Porphyria Agents
    - Givosiran
  - Amyloidosis Agents
    - Patisiran, Vutrisiran
  - Antilipemic Agents
    - Inclisiran
  - Duchenne Muscular Dystrophy Agents
    - Casimersen, Eteplirsen, Golodirsen, Viltolarsen
  - Hyperoxaluria Type 1 Agents
    - Lumasiran
- Cystic Fibrosis Agents
  - Ivacaftor, Lumacaftor, Tezacaftor
- Cystinosis Agents
  - Cysteamine
- Enzyme Replacement Therapy
  - Gaucher Disease Agents
    - Glucocerebrosidase (Enzyme Replacement Therapy)
      - Imiglucerase, Taliglucerase alfa, Velaglucerase alfa
    - Glucosylceramide Synthase Inhibitors (Substrate Restriction Therapy)
      - Eliglustat, Miglustat
  - Lysosomal Acid Lipase Deficiency Agents
    - Sebelipase alfa
  - Miscellaneous
  - Agalsidase beta, Alglucosidase alfa, Alpha1-Proteinase inhibitor, Elosulfase alfa, Galsulfase, Idursulfase, Laronidase, Pegademase
- Erythropoietic Protoporphyria Agents
  - Afamelanotide
- Fabry Disease Agents
  - Migalastat
- Hereditary Angioedema Agents
  - Berinert, Berotralstat, Cinryze, Danazol, Ecallantide, Haegarda, Icatibant, Lanadelumab, Ruconest
- Homocystinuria Agents
  - Betaine
- Huntington Disease Agents (for Chorea)
  - Vesicular Monoamine Transporter 2 (VMAT2) Inhibitors
    - Deutetrabenazine, Tetrabenazine, Valbenazine
- Monoclonal Antibodies
  - Burosumab
- Sickle Cell Disease Agents
  - Crizanlizumab, Hydroxyurea, L-Glutamine, Voxelotor
- Spinal Muscular Atrophy Agents
  - Risdiplam, Osmogene Abeparvovec
- Tyrosinemia Agents
  - Nitisinone
- Urea Cycle Disorder Agents
  - Carglumic Acid, Lactulose, Phenylbutyrate, Rifaximin, Sodium Benzoate
Glycopeptide Antibiotics
- Dalbavancin, Oritavancin, Telavancin, Vancomycin
Hematologic Agents Agents
- Myelodysplastic Syndrome Agents
  - Imetelstat
- Paroxysmal Nocturnal Hemoglobinuria
  - Pegcetacoplan
- See Antithrombotic Agents
- See Hematologic Growth Factors
- See Monoclonal Antibodies
- See Genetic Disorder Agents, Sickle Cell Disease Agents
Hematologic Growth Factors
- Colony Stimulating Factors
  - Granulocyte Colony Stimulating Factors
    - Filgrastim, Pegfilgrastim
  - Granulocyte-Macrophage Colony Stimulating Factors
    - Sargramostim
- Erythropoiesis Stimulating Agents
  - Daprodustat, Epoetin, Darbepoetin, Peginesatide
- Thrombopoietin Receptor Agonists and Thrombopoiesis Stimulators
  - Avatrombopag, Eltrombopag, Fostamatinib, Lusutrombopag, Romiplostim, Oprelvekin (IL-11)
- Miscellaneous
  - Luspatercept
Hepatitis C (HCV) Agents
- Interferon Based Therapies
  - Interferon A and Peginterferon, Interferon B, Ribavirin
- NS5A Inhibitors
  - Daclatasvir, Elbasvir, Ledipasvir, Ombitasvir, Pibrentasvir, Velpatasvir
- NS5B (Polymerase) Inhibitors
  - Dasabuvir, Sofosbuvir
- HCV Protease Inhibitors
  - Asunaprevir, Boceprevir, Glecaprevir, Grazoprevir, Paritaprevir, Simeprevir, Telaprevir, Voxilaprevir
- Combination Therapies
  - Epclusa, Harvoni, Mavyret, Technive, Viekira Pak, Vosevi, Zepatier
Herbal and Dietary Supplements
- Aloe Vera, Alpha Lipoic Acid, Apoaequorin, Areca Nut, Arnica Montana, Ashwagandha, Astragalus, Bacopa, Bee Products, Berberine, Bilberry, Bitter Melon, Black Cohosh, Black Cumin, Boswellia, Bromelain, Buchu, Butterbur, Cascara, Cat's Claw, Centella Asiatica, Chamomile, Chaparral, Chaste Tree, Chondroitin, Comfrey, Cranberry, Crofelemer, Dihydromyricetin, Dragon’s Blood, Echinacea, Ephedra, Eugenol, Fenugreek, Flavocoxid, Garcinia cambogia, Germander, Ginger, Ginkgo, Ginseng, Glucosamine, Grape Seed, Greater Celandine, Green Tea, Guarana, Hawthorn, Hoodia, Hops, Horny Goat Weed, Horse Chestnut, Horsetail, Hyssop, Kava Kava, Kelp, Khat, Kratom, Lavender, Lemon Balm, Licorice, Lion’s Mane, Maca, Margosa Oil, Melatonin, Milk Thistle, Mistletoe, Moringa, Noni, Nux Vomica, Oregano, Passionflower, Pennyroyal Oil, Quercetin, Red Yeast Rice, Resveratrol, Royal Jelly, Saw Palmetto, Senna, Skullcap, Slippery Elm, Spirulina, St. John's Wort, Stinging Nettle, Tara Flour, Tribulus, Turmeric, Usnic Acid, Uva Ursi, Valerian, Yohimbine
- Chinese and Other Asian Herbal Medicines
  - Ba Jiao Lian, Bol Gol Zhee, Chi R Yun, Jin Bu Huan, Ma Huang [Ephedra], Polygonum Multiflorum, Sho Saiko To and Dai Saiko To, Shou Wu Pian
- Multi-Ingredient Nutritional Supplements
  - Herbalife, Hydroxycut, Move Free, OxyELITE Pro, SLIMQUICK
- See also Nutritional Supplements
Hormonal Agents
- Growth Hormone Releasing Hormone (GHRH)
  - Tesamorelin
- Insulin
- Somatostatin Analogues
  - Lanreotide, Octreotide, Pasireotide
- See also Anabolic Steroids
- See also Antineoplastic Agents
- See also Corticosteroids
- See also Obstetrical and Gynecological Agents
- See also Osteoporosis Agents
- See also Thyroid Agents
Human Growth Hormone Deficiency Agents
- Somapacitan
Hypoglycemic Agents
- See Antidiabetic Agents
Ileal Bile Acid Transporter (IBAT) Inhibitors
- Maralixibat
- Odevixibat
Immunomodulatory Agents
- Efalizumab, Satralizumab
Immunosuppressive Agents
- Belimumab, Siltuximab, Voclosporin
Infertility Agents
- See Obstetrical and Gynecological Agents
Influenza Agents
- Amantadine, Baloxavir, Oseltamivir, Peramivir, Rimantadine, Zanamivir
Insomnia Agents
- See Sedatives and Hypnotics
Intermittent Claudication Agents
- Cilostazol, Pentoxifylline
Leishmaniasis Agents
- Miltefosine
Leprosy Agents
- Clofazimine, Dapsone, Rifampin
Lincosamides
- Clindamycin, Lincomycin
Linezolid
Lipid-Lowering Agents
- See Antilipemic Agents
Liver Disease Agents
- Elafibranor, Obeticholic Acid, Seladelpar, Ursodiol
Lysosomal Acid Lipase Deficiency Agents
- See Enzyme Replacement Therapy
Macrolide Antibiotics
- Azithromycin, Clarithromycin, Erythromycin, Fidaxomicin, Telithromycin
Macular Degeneration Agents
- Aflibercept, Avacincaptad pegol, Bevacizumab, Brolucizumab, Faricimab, Pegaptanib, Pegcetacoplan, Ranibizumab
Methotrexate
Metronidazole
Migraine Headache Agents
- Ergot Alkaloids
  - Ergotamine, Dihydroergotamine
- Monoclonal Antibodies
  - Eptinezumab, Erenumab, Fremanezumab, Galcanezumab
- Triptans
  - Almotriptan, Eletriptan, Frovatriptan, Naratriptan, Rizatriptan, Sumatriptan, Zolmitriptan
- Miscellaneous
  - Lasmiditan, Rimegepant, Ubrogepant
Monoclonal Antibodies
- Alzheimer Disease Agents
  - Aducanumab, Lecanemab
- Antiasthmatic Agents
  - Benralizumab, Dupilumab, Mepolizumab, Omalizumab, Reslizumab, Tezepelumab
- Antidiabetic Agents
  - Teplizumab
- Antiinfective Agents
  - Antitoxins
    - Bezlotoxumab, Obiltoxaximab, Raxibacumab
- Antilipemic Agents, Anti-PCSK9
  - Alirocumab, Evinacumab (Anti-ANGPTL3), Evolocumab
- Antineoplastic Agents
  - Alemtuzumab, Atezolizumab, Avelumab, Belantamab, Bevacizumab, Blinatumomab, Brentuximab, Cemiplimab, Cetuximab, Daratumumab, Dinutuximab, Dostarlimab, Durvalumab, Elotuzumab, Enfortumab, Gemtuzumab, Inotuzumab Ozogamicin, Ipilimumab, Margetuximab, Mogamulizumab, Moxetumomab Pasudotox, Naxitamab, Necitumumab, Nivolumab, Ofatumumab, Olaratumab, Panitumumab, Pembrolizumab, Pertuzumab, Polatuzumab Vedotin, Ramucirumab, Rituximab, Sacituzumab Govitecan, Tafasitamab, Teclistamab, Tisotumab Vedotin, Tositumomab, Trastuzumab, Trastuzumab Deruxtecam, Trastuzumab Emtansine, Tremelimumab
- Antirheumatic Agents
  - Adalimumab, Canakinumab, Certolizumab, Golimumab, Infliximab, Rituximab, Sarilumab, Tocilizumab, Ustekinumab
- Antithyroid Agents
  - Teprotumumab (for Graves ophthalmopathy)
- Antiviral Agents
  - Ibalizumab
- Atopic Dermatitis Agents
  - Dupilumab, Tralokinumab
- COVID-19 Agents
  - Bamlanivimab, Casirivimab, Etesevimab, Imdevimab, Sotrovimab
- Ebolavirus Agents
  - REGN-EB3 – Atoltivimab, Maftivimab, Odesivimab
- Genetic Disorder Agents
  - Burosumab
- Hematologic Agents
  - Caplacizumab, Eculizumab, Emapalumab, Emicizumab, Lanadelumab, Ravulizumab
- Immunomodulatory/Immunosuppressive Agents
  - Anifrolumab, Belimumab, Efalizumab, Satralizumab, Siltuximab
- Inflammatory Bowel Disease Agents
  - Adalimumab, Certolizumab, Golimumab, Infliximab, Vedolizumab
- Macular Degeneration Agents
  - Bevacizumab, Brolucizumab, Faricimab, Ranibizumab
- Migraine Headache Agents
  - Eptinezumab, Erenumab, Fremanezumab, Galcanezumab
- Multiple Myeloma Agents
  - Isatuximab
- Multiple Sclerosis Agents
  - Alemtuzumab, Natalizumab, Ocrelizumab
- Neurological Disease Agents
  - Inebilizumab
- Osteoporosis Agents
  - Denosumab, Romosozumab
- Psoriasis Agents
  - Adalimumab, Brodalumab, Certolizumab, Efalizumab, Etanercept, Golimumab, Guselkumab, Infliximab, Ixekizumab, Risankizumab, Secukinumab, Tildrakizumab, Ustekinumab
- Transplant Agents
  - Alemtuzumab, Basiliximab, Daclizumab, Muromonab
Multiple Sclerosis Agents
- Alemtuzumab, Dalfampridine, Dimethyl Fumarate, Diroximel Fumarate, Fingolimod, Glatiramer Acetate, Interferon Beta, Mitoxantrone, Monomethyl Fumarate, Natalizumab, Ocrelizumab, Ozanimod, Ponesimod, Siponimod, Teriflunomide
Muscle Relaxants
- Baclofen, Carisoprodol, Chlorzoxazone, Cyclobenzaprine, Dantrolene, Metaxalone, Methocarbamol, Orphenadrine, Quinine, Tizanidine
Myasthenia Agents
- Amifampridine
- Anticholinesterase Inhibitors
  - Neostigmine, Pyridostigmine
Narcotic Antagonists
- See Opioids, Opioid Antagonists
Narcotics
- See Opioids, Opioid Antagonists
Nitrofurantoin
Nonsteroidal Antiinflammatory Drugs (NSAIDs)
- Acetaminophen, Celecoxib, Diclofenac, Diflunisal, Etodolac, Fenoprofen, Flurbiprofen, Ibuprofen, Indomethacin, Ketoprofen, Ketorolac, Mefenamic Acid, Meloxicam, Metamizole, Nabumetone, Naproxen, Nimesulide, Oxaprozin, Phenylbutazone, Piroxicam, Rofecoxib, Sulindac, Tolmetin
Nutritional Supplements
- Chondroitin, Coenzyme Q10, Docosahexaenoic Acid, Eicosapentaenoic Acid, Glucosamine, alpha-Linolenic Acid, Omega-3 Fatty Acids, Triheptanoin
Obstetrical and Gynecological Agents
- Emergency Contraceptive Agents
  - Levonorgestrel, Ulipristal
- Endometriosis and Menstrual Conditions
  - Gonadotropin Releasing Hormone Antagonists
    - Elagolix
- Estrogens and Oral Contraceptives
  - Selective Estrogen Receptor Modulators
    - Bazedoxifene, Ospemifene, Raloxifene
- Infertility Agents
  - Antiestrogens
    - Clomiphene, Letrozole, Tamoxifen
  - Gonadotropins
    - Chorionic Gonadotropin, Follicle Stimulating Hormone, Luteinizing Hormone, Human Gonadotropin Releasing Hormone
- Pregnancy Termination Agents
  - Mifepristone
- Progesterone and the Progestins
Opioids, Opioid Antagonists
- Full and Partial Agonists
  - Alfentanil, Butorphanol, Codeine, Diphenoxylate, Fentanyl, Heroin, Hydrocodone, Hydromorphone, Levorphanol, Loperamide, Meperidine, Methadone, Morphine, Oliceridine, Opium, Oxycodone, Oxymorphone, Pentazocine, Remifentanil, Sufentanil, Tramadol
- Opioid Antagonists
  - Naldemedine, Nalmefene, Naloxegol, Naloxone, Naltrexone
Osteoporosis Agents
- Bisphosphonates
  - Alendronate, Etidronate, Ibandronate, Pamidronate, Risedronate, Zoledronic Acid
- Hormonal Agents
  - Calcitonin, Teriparatide
  - Selective Estrogen Receptor Modulators
    - Bazedoxifene, Raloxifene
- Monoclonal Antibodies
  - Denosumab, Romosozumab
Parkinson Disease Agents
- Anticholinergic Agents
  - Benztropine, Biperiden, Trihexyphenidyl
- COMT Inhibitors
  - Entacapone, Opicapone, Tolcapone
- Dopamine Precursors
  - Levodopa and Carbidopa
- Dopamine Receptor Agonists
  - Apomorphine, Bromocriptine, Pergolide, Pramipexole, Ropinirole, Rotigotine
- Selective MAO Inhibitors
  - Rasagiline, Safinamide, Selegiline
- Others
  - Amantadine, Diphenhydramine, Droxidopa, Istradefylline , Pimavanserin, Rivastigmine
Penicillins, First Generation (Natural Penicillins)
- Benzathine Penicillin, Procaine Penicillin, Penicillin G, Penicillin V, Penicillin VK
Penicillins, Second Generation (Penicillinase-Resistant Penicillins)
- Cloxacillin, Dicloxacillin, Flucloxacillin, Methicillin, Nafcillin, Oxacillin
Penicillins, Third Generation (Aminopenicillins)
- Amoxicillin, Ampicillin, Ampicillin-Sulbactam, Bacampicillin, Pivampicillin
- See also Amoxicillin-Clavulanate
Penicillins, Fourth Generation (Extended-Spectrum Penicillins)
- Carbenicillin, Mezlocillin, Piperacillin, Piperacillin-Tazobactam, Ticarcillin, Ticarcillin-Clavulanate
Pharmacokinetic Enhancers [Primary Agent]
- Avibactam [Ceftazidime], Carbidopa [Levodopa], Cilasta, in [Imipenem], Clavulanic Acid [Amoxicillin, Ticarcillin], Cobicistat [Atazanavir, Darunavir, Elvitegravir], Ritonavir [Lopinavir, Paritaprevir], Sulbactam [Ampicillin], Tazobactam [Piperacillin], Tipiracil [Trifluridine]
Phosphodiesterase Type 5 (PDE5) Inhibitors
- Avanafil, Sildenafil, Tadalafil, Vardenafil
Protein Kinase Inhibitors
- Abemaciclib, Abrocitinib, Acalabrutinib, Adagrasib, Afatinib, Alectinib, Alpelisib, Asciminib, Avapritinib, Axitinib, Baricitinib, Belumosudil, Binimetinib, Bortezomib, Bosutinib, Brigatinib, Cabozantinib, Capmatinib, Carfilzomib, Ceritinib, Cobimetinib, Copanlisib, Crizotinib, Dabrafenib, Dacomitinib, Dasatinib, Deucravacitinib, Duvelisib, Enasidenib, Encorafenib, Entrectinib, Erdafitinib, Erlotinib, Fedratinib, Fostamatinib, Futibatinib, Gefitinib, Gilteritinib, Glasdegib, Ibrutinib, Idelalisib, Imatinib, Infigratinib, Ivosidenib, Ixazomib, Lapatinib, Larotrectinib, Lenvatinib, Leniolisib, Lorlatinib, Midostaurin, Mobocertinib, Momelotinib, Neratinib, Nilotinib, Niraparib, Olaparib, Olutasidenib, Osimertinib, Pacritinib, Palbociclib, Pazopanib, Pemigatinib, Pexidartinib, Pirtobrutinib, Ponatinib, Pralsetinib, Quizartinib, Regorafenib, Ribociclib, Ripretinib, Ritlecitinib, Rucaparib, Ruxolitinib, Selpercatinib, Selumetinib, Sonidegib, Sorafenib, Sotorasib, Sunitinib, Talazoparib, Tepotinib, Tivozanib, Tofacitinib, Trametinib, Trilaciblib, Tucatinib, Umbralisib, Upadacitinib, Vandetanib, Vemurafenib, Vismodegib, Zanubrutinib
- See also Antineoplastic Agents; Antirheumatic Agents; Hematologic Growth Factors; Macular Degeneration Agents
Psoriasis Agents
- See Dermatologic Agents
Pulmonary Disease Agents
- Chronic Obstructive Pulmonary Disease (COPD) Agents
  - Anticholinergic Agents
    - Ipratropium, Tiotropium, Aclidinium
  - Beta-2 Adrenergic Agonists
    - Albuterol, Formoterol, Salmeterol, Terbutaline
  - Corticosteroids
    - Budesonide, Fluticasone
  - Miscellaneous
    - Roflumilast, Theophylline
- Pulmonary Arterial Hypertension Agents
- Pulmonary Fibrosis Agents
  - Nintedanib, Pirfenidone
Rifaximin
Salicylates
- Aspirin, Diflunisal, Salsalate, Trisalicylate
Sedatives and Hypnotics
- Antihistamines
  - Diphenhydramine, Doxylamine, Hydroxyzine
- Barbiturates
  - Amobarbital, Butabarbital, Phenobarbital, Secobarbital
- Benzodiazepines
  - Alprazolam, Diazepam (Intravenous), Diazepam (Oral), Estazolam, Flurazepam, Quazepam, Remimazolam, Temazepam, Triazolam
- Benzodiazepine Receptor Agonists
  - Eszopiclone, Zaleplon, Zolpidem
- Herbals
  - Chamomile (Matricaria recutita), Hops (Humulus lupulus), Lavender (Lavandula angustifolia), Passionflower (Passiflora incarnata), Valerian (Valeriana officinalis)
- Melatonin and its Analogues
  - Melatonin, Ramelteon, Tasimelteon
- Miscellaneous
  - Buspirone, Chloral Hydrate, Doxepin, Lemborexant, Meprobamate, Oxybate (Narcolepsy Agent), Suvorexant
Sjögren Syndrome Agents
- Cholinergic Agents
  - Cevimeline, Pilocarpine
Statins
- Atorvastatin, Fluvastatin, Lovastatin, Pravastatin, Rosuvastatin, Simvastatin
Substance Abuse Treatment Agents
- Acamprosate, Buprenorphine, Disulfiram, Methadone, Nalmefene, Naloxegol, Naloxone, Naltrexone, Nicotine, Varenicline
Sulfonamides
- Dapsone, Sulfadiazine, Sulfadoxine-Pyrimethamine, Sulfamethoxazole-Trimethoprim, Sulfasalazine, Sulfinpyrazone, Sulfisoxazole
Tamoxifen
Tetracyclines
- Demeclocycline, Doxycycline, Eravacycline, Minocycline, Omadacycline, Sarecycline, Tetracycline, Tigecycline
Thalidomide
Thyroid and Antithyroid Agents
- Thyroid Agents
  - Thyroid Hormone, Levothyroxine, Liothyronine
- Antithyroid Agents
  - Methimazole, Propylthiouracil; Teprotumumab (for Graves ophthalmopathy)
Tibolone
Trace Elements and Metals
- Arsenic, Bismuth, Cadmium, Chromium, Copper, Fluoride, Iodine, Iron, Lead, Lithium, Manganese, Mercury, Molybdenum, Nickel, Selenium, Silicon, Tin, Vanadium, Zinc
Transplant Agents
- Antithymocyte Globulin
- Cyclosporine, Everolimus, Mycophenolate, Sirolimus, Tacrolimus
- Monoclonal Antibodies
  - Alemtuzumab, Basiliximab, Daclizumab, Muromonab
- Plerixafor
Tumor Necrosis Factor Antagonists
- Adalimumab, Certolizumab, Etanercept, Golimumab, Infliximab
Tyrosine Kinase Receptor Inhibitors
- Axitinib, Bortezomib, Bosutinib, Carfilzomib, Crizotinib, Dabrafenib, Dasatinib, Erlotinib, Gefitinib, Ibrutinib, Imatinib, Lapatinib, Nilotinib, Pazopanib, Ponatinib, Regorafenib, Ruxolitinib, Sorafenib, Sunitinib, Tofacitinib, Trametinib, Vandetanib, Vemurafenib, Vismodegib
Urologic Agents
- Overactive Bladder Syndrome Agents
  - Darifenacin, Fesoterodine, Flavoxate, Hyoscyamine, Mirabegron, Oxybutynin, Solifenacin, Tolterodine, Trospium, Vibegron
Vancomycin
Vinca Alkaloids
- Vinblastine, Vincristine, Vinorelbine
Vitamins
- Folic Acid (Folate, Folinic Acid)
- Vitamin A & Retinoids
- Vitamin B
  - Biotin, Choline, Cyanocobalamin, Niacin (Nicotinamide, Nicotinic Acid), Pantothenic Acid, Pyridoxine, Riboflavin, Thiamine
- Vitamin C (Ascorbic Acid)
- Vitamin D (Cholecalciferol, Ergocalciferol)
- Vitamin E (alpha Tocopherol)
- Vitamin K (Menadione, Phytonadione)
Weight Loss Agents
- Diethylpropion, Lorcaserin, Naltrexone-Bupropion, Orlistat, Phentermine, Phentermine-Topiramate, Setmelanotide, Sibutramine

Bookshelf ID: NBK569838

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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Agents Included in LiverTox by Drug Class. [Updated 2024 Oct 9].
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