NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
National Guideline Centre (UK). Emergency and acute medical care in over 16s: service delivery and organisation. London: National Institute for Health and Care Excellence (NICE); 2018 Mar. (NICE Guideline, No. 94.)
Emergency and acute medical care in over 16s: service delivery and organisation.
Show details18. Minor injury unit, urgent care centre or walk-in centre
18.1. Introduction
Minor Injuries Units, Walk-in centres and Urgent Care centres are all services that are not designed to treat patients with an acute medical emergency (AME). The important common features of these services for this guideline are that they provide walk-in access without the need for pre-registration, but they are not Emergency Departments with “Majors” or “Resuscitation” areas receiving acute medical emergencies. Their potential significance in the treatment of patients with an AME arises from reducing ED demand by treating patients who do not have an AME. It is also an important question to address the following hypothetical considerations:
- Can Minor Injuries units (MIU), Walk-in centres (WiC), or Urgent Care centres (UCC) reduce the demand on Emergency departments (ED) by treating patients who do not have an AME, and thereby improve access and responsiveness for patients with an AME when they attend hospital?
- What are the causes and consequences of patients with acute medical emergencies who attend MIU, WiC or UCC when they should have presented urgently to an ED?
- Mild acute medical emergencies?
18.2. Review question: Is a minor injury unit, urgent care centre or walk-in centre clinically and cost effective: 1. as a standalone unit 2. when co-located on the same site as a full emergency department?
For full details see review protocol in Appendix A.
Table 1
PICO characteristics of review question.
18.3. Clinical evidence
Five before-after studies were included in the review;1,9,10,15,21,35 these are summarised in Table 2 below. Evidence from these studies is summarised in the clinical evidence summary below (Table 3). See also the study selection flow chart in Appendix B, study evidence tables in Appendix D, forest plots in Appendix C, GRADE tables in Appendix F and excluded studies list in Appendix G.
Table 2
Summary of studies included in the review.
Table 3
Clinical evidence summary: Stand-alone units (walk-in centres) versus absence.
Table 4
Clinical evidence summary: Co-located (walk-in centres and minor injury units) on the same site as the ED versus absence.
18.4. Economic evidence
Published literature
One economic evaluation was identified with the relevant comparison and has been included in this review.35 This is summarised in the economic evidence profiles below (Table 5) and the economic evidence tables in Appendix E.
Table 5
Economic evidence profile: walk-in centre (stand-alone or co-located) versus none.
The economic article selection protocol and flow chart for the whole guideline can found in the guideline’s Appendix 41A and Appendix 41B.
18.5. Evidence statements
Clinical
Stand-alone walk-in centre versus absence
Three studies (number of participants not reported) evaluated stand-alone walk-in centres for improving outcomes in secondary care in adults and young people at risk of an AME, or with a suspected or confirmed AME. The evidence suggested that stand-alone walk-in centres may provide a benefit in ED avoidance expressed as mean monthly attendance rates (2 studies, very low quality). However, the evidence suggested that there was no effect on ED avoidance expressed as annual non-ambulance attendance rates; per 1000 population (1 study, very low quality). The evidence for ED avoidance was inconsistent due to different reported methodologies (mean and rate ratio reported separately).
Co-located (MIU/walk-in centres) on the same site as the ED versus absence
Walk-in centres
One study (number of participants not reported) evaluated EDs with co-located walk-in centres for improving outcomes in secondary care in adults and young people at risk of an AME, or with a suspected or confirmed AME. The evidence suggested that co-located walk-in centres may provide a benefit in terms of ED avoidance mean monthly attendance rates (very low). There was a possible increase in ED avoidance patient throughput expressed as mean monthly attendances (very low quality). The evidence suggested there was no effect on avoidable adverse events (low quality).
Minor-injury units
One study comprising 584,321participants evaluated co-located minor injury units for improving outcomes in secondary care in adults and young people at risk of an AME, or with a suspected or confirmed AME. The organisation of the minor injury unit was not defined, other than stating that there were no major changes in staffing levels before and after its introduction. The evidence suggested there was no effect on waiting time in ED and mortality (low quality).
Economic
One comparative cost analysis found that co-located walk-in centres are less costly compared to emergency department (cost saving: £3.06 per patient). This analysis was assessed as partially applicable with potentially serious limitations.
18.6. Recommendations and link to evidence
| Recommendations | - |
| Research recommendations | RR10. Is a minor injury unit, urgent care or walk-in centre clinically and cost effective i) as a standalone unit and ii) when located on the same site as an emergency department? |
| Relative values of different outcomes |
Avoidable adverse events (including redirection of care to another urgent care provider), quality of life, patient and/or carer satisfaction, waiting time in ED, including A&E 4 hour waiting time target, and mortality were considered by the guideline committee to be critical outcomes. ED avoidance was considered to be an important outcome. |
| Trade-off between clinical benefits and harms |
There was evidence from 5 observational studies; 3 studies compared standalone walk-in centres with no stand-alone walk-in centres, 1 study compared EDs with co-located walk-in centres with EDs without co-located walk-in centres and 1 study compared co-located minor injury units with absence of co-located minor injury units. Stand-alone units Minor injury units No evidence was found specifically for stand-alone minor injury units, although the nomenclature and the definitions appear very interchangeable. Urgent care centres No evidence was found specifically for stand-alone urgent care centres, although the nomenclature and the definitions appear very interchangeable. Walk-in centres There was evidence from 3 studies comparing stand-alone walk-in centres with absence of stand-alone walk-in centres. The evidence suggested that stand-alone walk-in centres may provide a benefit in terms of ED avoidance (mean monthly attendance rates). However, there was no effect on ED avoidance expressed as annual non-ambulance attendance rates per 1000 population. The evidence for ED avoidance was inconsistent due to different reported methodologies (mean and rate ratio were reported separately). There was no evidence for avoidable adverse events, re-consultation, quality of life, patient and/or carer satisfaction, waiting time in ED and mortality. The committee highlighted the importance of how the units or centres were defined by the studies in their consideration of the evidence. With regard to studies comparing stand-alone walk-in centres with absence of a walk-in centre, 1 study was based on a GP-led walk-in centre, open from 8am to 9pm, 7 days a week; 1 study assessed the impact of 10 different walk-in centres, which varied in terms of setting, available services and staffing; the other study did not specify details about staffing or set-up, other than that it shared the same premises, entrance and triage process as a minor injuries unit. Co-located units: Urgent care centres No evidence was found for co-located urgent care centres. Walk-in centres One study (number of participants not reported) suggested that co-located walk-in centres provided benefits in terms of ED avoidance mean monthly attendance rates. The evidence suggested there was an increase in ED avoidance patient throughput (mean monthly attendances). There was no effect on avoidable adverse events. There was no evidence available for re-consultation, quality of life, patient and/or carer satisfaction and mortality. Minor-injury units One study comprising 584,321 participants evaluated co-located minor injury units for improving outcomes in secondary care. The organisation of the minor injury unit was not defined, other than stating that there were no major changes in staffing levels before and after its introduction. The evidence suggested there was no effect on waiting time in ED and mortality. There was no evidence available for ED avoidance, avoidable adverse events, re-consultation, quality of life and patient and/or carer satisfaction. Given the lack of evidence for avoidable adverse events, quality of life, patient and/or carer satisfaction and mortality and the heterogeneous evidence for ED avoidance, the committee did not consider increased compliance with the A&E 4 hour waiting time target alone to be sufficient to justify a recommendation. The committee therefore decided not to make a recommendation for minor injury units, urgent care centres or walk-in centres. However, there was no evidence to suggest that these units are harmful. Based on the heterogeneity of the models used in the studies and the lack of consistent evidence, the committee agreed that more evidence is required to inform a recommendation. It was therefore decided to recommend that further research should be carried out. |
| Trade-off between net effects and costs |
One comparative cost analysis was included which compared emergency departments before and after the introduction of co-located walk-in centres with matched control emergency departments. The study showed a modest cost saving in the mean cost per patient in the base-case analysis (£3), and therefore it might be cost-effective if outcomes are at least similar. However, the study did not give a clear description of the staffing models used in these walk-in centres. The follow-up in the study was short, with the cost analysis conducted for a period of 3 months; hence it may not have captured differences in down-stream costs. Together with the lack of a clear benefit for walk-in centres from the clinical evidence review, the committee considered the evidence to support recommending wider implementation of co-located walk-in-centres to be weak. There was no economic evidence for either MIUs or UCCs, so the unit costs of visits to these centres from the NHS reference costs were also presented to the committee. It was noted that in the NHS reference costs, the weighted average unit cost of a MIU/UCC visit or walk-in-centre visit (£67 or £46) is less costly than an ED visit (£114). The committee also discussed the current practice in the NHS and reflected that there is variation in how MIUs, UCCs and WiCs are run across the country, which makes it difficult to recommend a specific service configuration and staffing model. The committee noted that co-location of these units within an ED should allow for economies of scale in terms of sharing resources with the ED (that is, flexing of staff to demand); however, co-location may not always be practical especially in rural areas. Additionally, a concern was expressed that the presence of these units might result in a supplier-induced demand that is, more presentations by people who could have managed without professional intervention, or who could have attended their GP. Overall, the committee felt that the evidence available was insufficient to support a recommendation for wider implementation within the NHS, preferring instead to make a research recommendation to assess the clinical and cost-effectiveness of these models of care. |
| Quality of evidence |
All included studies were observational study designs. For the comparison between stand-alone units versus absence and co-located units versus absence, the evidence was considered to be of low to very low quality due to the high risk of bias and imprecision. The economic evidence was rated as partially applicable with potentially serious limitations. The included study is a comparative cost analysis; hence, QALYs were not used as an outcome measure. There was also uncertainty regarding the applicability of resource use and costs from 2004-2005 to current NHS context. The study had a short follow-up period (cost data analysed for 3 months before and 3 months after the introduction co-located walk-in-centre), so follow-up may not have been long enough to capture all relevant differences in costs and outcomes. Sources of unit costs are not reported and may not be reflective of national unit costs. |
| Other considerations |
Over the last 30 years the NHS has have opened ‘walk-in centres’, ‘minor injury units’, ‘urgent care centres’ and a substantial range of similarly-named facilities that all offer slightly different services, at slightly different times, in different places. This has resulted in a very confusing system for patients. There appears to be no specific definition for any of these units or centres. An NHS “walk-in centre” is defined by Monitor as a site that provides routine and urgent primary care for minor ailments and injuries with no requirement for patients to pre-book an appointment or to be registered at the centre or with any GP practice. The Dudley Group NHS Foundation Trust defines an “urgent care centre” as a unit that offers non-emergency care for walk-in patients who have minor illnesses and injuries that need urgent attention. North Devon Healthcare Trust defines a “minor injuries unit” as a department largely staffed by emergency nurse practitioners (ENPs) working autonomously who look after minor injuries such as lacerations and fractures, and have access to X-ray facilities. NHS choices does not appear to differentiate between the 3 types of units or centres. Walk-in centres (WICs), were established in England in 2009 to improve access to GPs as well as to prevent unnecessary attendances at ED by having extended opening hours and being placed in a convenient location. There are many units located in the major cities particularly in London. There is no clear definition of what staffing arrangement comprises a walk-in centre, a minor injuries unit or an urgent care centre. There is variability across different units and areas in terms of opening hours, staffing, resources and location (either co-located or stand-alone). All of these factors have a significant impact on case mix. The committee noted the following definitions applicable to different types of A&E departments27:
It was agreed that the absence of a consistent terminology for structures and processes and also the level and type of staffing relating to MIUs, UCCs and WiCs makes their evaluation challenging. Future studies should take into account several contextual factors including location (inner-city, urban and rural), opening times (24 hour versus restricted times) staffing composition and expertise, available resources, processes and overall service configuration in their analyses. Proximity to these units could be used as an instrumental variable to evaluate outcomes given the impossibility of randomising populations. The majority of the evidence came from studies with relatively short follow up periods, which the committee considered to be a significant limitation as it may not reflect long term effects. Future studies evaluating effects over longer time frames would offer the opportunity to account for secular trends and detect population effects. As well as ED demand, other outcomes should be patient-focussed and rooted in health economics evaluation. The potential impact on other services such as the ambulance service (particularly within rural areas) should be evaluated. Staff exposure to specific health problems within the ED may be reduced as a result of streaming particular groups of patients to specialist centres. Therefore, it would also be useful to assess the impact on staff training and potential staff de-skilling. In summary, the current level of evidence is insufficient to permit a recommendation on the internal or external configuration of such units. Opportunities should be taken to evaluate MIUs, UCCs and WICs using existing services or if local health economies choose to implement such services. |
References
- 1.
- Arain M, Campbell MJ, Nicholl JP. Impact of a GP-led walk-in centre on NHS emergency departments. Emergency Medicine Journal. 2015; 32(4):295–300 [PubMed: 24406328]
- 2.
- Banerjee J, Benger J, Treml J, Martin FC, Grant R, Lowe D et al. The National Falls and Bone Health Audit: implications for UK emergency care. Emergency Medicine Journal. 2012; 29(10):830–832 [PubMed: 22045604]
- 3.
- Beales J, Baker B. Minor Injuries Unit: expanding the scope of accident and emergency provision. Accident and Emergency Nursing. 1995; 3(2):65–67 [PubMed: 7773716]
- 4.
- Bickerton J, Davies J, Davies H, Apau D, Procter S. Streaming primary urgent care: a prospective approach. Primary Health Care Research and Development. 2012; 13(2):142–152 [PubMed: 21774867]
- 5.
- Bickerton J, Dewan V, Allan T. Streaming A&E patients to walk-in centre services. Emergency Nurse. 2005; 13(3):20–23 [PubMed: 15974151]
- 6.
- Byrne G, Richardson M, Brunsdon J, Patel A. An evaluation of the care of patients with minor injuries in emergency settings. Accident and Emergency Nursing. 2000; 8(2):101–109 [PubMed: 10818377]
- 7.
- Caspers C, Smith SW, Seth R, Femia R, Goldfrank LR. Observation services linked with an urgent care center in the absence of an emergency department: an innovative mechanism to initiate efficient health care delivery in the aftermath of a natural disaster. Disaster Medicine and Public Health Preparedness. 2016; 10(3):405–410 [PubMed: 27087398]
- 8.
- Castledine G. Overzealousness in accident and emergency nursing. British Journal of Nursing. 2008; 17(18):1199 [PubMed: 18946400]
- 9.
- Chalder M, Montgomery A, Hollinghurst S, Cooke M, Munro J, Lattimer V et al. Comparing care at walk-in centres and at accident and emergency departments: an exploration of patient choice, preference and satisfaction. Emergency Medicine Journal. 2007; 24(4):260–264 [PMC free article: PMC2658231] [PubMed: 17384379]
- 10.
- Chalder M, Sharp D, Moore L, Salisbury C. Impact of NHS walk-in centres on the workload of other local healthcare providers: time series analysis. BMJ. 2003; 326(7388):532 [PMC free article: PMC150465] [PubMed: 12623914]
- 11.
- Chapman JL, Zechel A, Carter YH, Abbott S. Systematic review of recent innovations in service provision to improve access to primary care. British Journal of General Practice. 2004; 54(502):374–381 [PMC free article: PMC1266174] [PubMed: 15113523]
- 12.
- Dale J, Dolan B. Do patients use minor injury units appropriately? Journal of Public Health Medicine. 1996; 18(2):152–156 [PubMed: 8816312]
- 13.
- Davis C. No waiting in vein. Nursing Standard. 2005; 20(11):22–24 [PubMed: 16320958]
- 14.
- Desborough J, Forrest L, Parker R. Nurse-led primary healthcare walk-in centres: an integrative literature review. Journal of Advanced Nursing. 2012; 68(2):248–263 [PubMed: 21834837]
- 15.
- Freeman JV, Croft S, Cross S, Yap C, Mason S. The impact of the 4 h target on patient care and outcomes in the Emergency Department: an analysis of hospital incidence data. Emergency Medicine Journal. 2010; 27(12):921–927 [PubMed: 20466827]
- 16.
- Freij RM, Duffy T, Hackett D, Cunningham D, Fothergill J. Radiographic interpretation by nurse practitioners in a minor injuries unit. Journal of Accident and Emergency Medicine. 1996; 13(1):41–43 [PMC free article: PMC1342607] [PubMed: 8821226]
- 17.
- Gnani S, Ramzan F, Ladbrooke T, Millington H, Islam S, Car J et al. Evaluation of a general practitioner-led urgent care centre in an urban setting: description of service model and plan of analysis. JRSM Short Reports. 2013; 4(6):2042533313486263 [PMC free article: PMC3697860] [PubMed: 23885294]
- 18.
- Grant C, Nicholas R, Moore L, Salisbury C. An observational study comparing quality of care in walk-in centres with general practice and NHS Direct using standardised patients. BMJ. 2002; 324(7353):1556 [PMC free article: PMC116613] [PubMed: 12089094]
- 19.
- Gray A, Gill S, Airey M, Williams R. Descriptive epidemiology of adult critical care transfers from the emergency department. Emergency Medicine Journal. 2003; 20(3):242–246 [PMC free article: PMC1726082] [PubMed: 12748139]
- 20.
- Heaney D, Paxton F. Evaluation of a nurse-led minor injuries unit. Nursing Standard. 1997; 12(4):35–38 [PubMed: 9392278]
- 21.
- Hsu RT, Lambert PC, Dixon-Woods M, Kurinczuk JJ. Effect of NHS walk-in centre on local primary healthcare services: before and after observational study. BMJ. 2003; 326(7388):530 [PMC free article: PMC150464] [PubMed: 12623913]
- 22.
- Ismail SA, Gibbons DC, Gnani S. Reducing inappropriate accident and emergency department attendances: a systematic review of primary care service interventions. British Journal of General Practice. 2013; 63(617):E813–E820 [PMC free article: PMC3839390] [PubMed: 24351497]
- 23.
- Jackson CJ, Dixon-Woods M, Hsu R, Kurinczuk JJ. A qualitative study of choosing and using an NHS Walk-in Centre. Family Practice. 2005; 22(3):269–274 [PubMed: 15805129]
- 24.
- Land L, Meredith N. An evaluation of the reasons why patients attend a hospital Emergency Department. International Emergency Nursing. 2013; 21(1):35–41 [PubMed: 23273802]
- 25.
- Marshall C. NATN/3M Award. Telephone logging and walk-in clinic. British Journal of Theatre Nursing. 1998; 8(6):8–10 [PubMed: 9934039]
- 26.
- McIntosh KL. Walk-in clinics. Leadership in Health Services. 1996; 5(3):13–14 [PubMed: 10158403]
- 27.
- NHS England. Emergency care weekly situation report definitions, 2014. Available from: https://www
.england.nhs .uk/statistics/wp-content /uploads/sites /2/2013/03/EC-Weekly-Sitrep-Definitions-v1.0.doc - 28.
- Paxton F, Heaney D. Minor injuries units: evaluating patients’ perceptions. Nursing Standard. 1997; 12(5):45–47 [PubMed: 9392296]
- 29.
- Roberts E, Mays N. Can primary care and community-based models of emergency care substitute for the hospital accident and emergency (A & E) department? Health Policy. 1998; 44(3):191–214 [PubMed: 10182293]
- 30.
- Rourke T, Tassone P, Philpott C, Bath A. ENT cases seen at a local ‘walk-in centre’: a one year review. Journal of Laryngology and Otology. 2009; 123(3):339–342 [PubMed: 18485251]
- 31.
- Rudge GM, Mohammed MA, Fillingham SC, Girling A, Sidhu K, Stevens AJ. The combined influence of distance and neighbourhood deprivation on Emergency Department attendance in a large English population: a retrospective database study. PloS One. 2013; 8(7):e67943 [PMC free article: PMC3712987] [PubMed: 23874473]
- 32.
- Sakr M, Kendall R, Angus J, Sanders A, Nicholl J, Wardrope J et al. Emergency nurse practitioners: a three part study in clinical and cost effectiveness. Emergency Medicine Journal. 2003; 20(2):158–163 [PMC free article: PMC1726060] [PubMed: 12642530]
- 33.
- Salisbury C. Do NHS walk-in centres in England provide a model of integrated care? International Journal of Integrated Care. 2003; 3:e18 [PMC free article: PMC1483943] [PubMed: 16896375]
- 34.
- Salisbury C, Chalder M, Scott TM, Pope C, Moore L. What is the role of walk-in centres in the NHS? BMJ. 2002; 324(7334):399–402 [PMC free article: PMC65536] [PubMed: 11850372]
- 35.
- Salisbury C, Hollinghurst S, Montgomery A, Cooke M, Munro J, Sharp D et al. The impact of co-located NHS walk-in centres on emergency departments. Emergency Medicine Journal. 2007; 24(4):265–269 [PMC free article: PMC2658232] [PubMed: 17384380]
- 36.
- Salisbury C, Manku-Cott T, Moore L, Chalder M, Sharp D. Questionnaire survey of users of NHS walk-in centres: observational study. British Journal of General Practice. 2002; 52(480):554–560 [PMC free article: PMC1314357] [PubMed: 12120727]
- 37.
- Salisbury C, Munro J. Walk-in centres in primary care: a review of the international literature. British Journal of General Practice. 2003; 53(486):53–59 [PMC free article: PMC1314495] [PubMed: 12564280]
- 38.
- Simpson AN, Wardrope J, Burke D. The Sheffield experiment: the effects of centralising accident and emergency services in a large urban setting. Emergency Medicine Journal. 2001; 18(3):193–197 [PMC free article: PMC1725596] [PubMed: 11354211]
- 39.
- Snooks H, Foster T, Nicholl J. Results of an evaluation of the effectiveness of triage and direct transportation to minor injuries units by ambulance crews. Emergency Medicine Journal. 2004; 21(1):105–111 [PMC free article: PMC1756342] [PubMed: 14734396]
- 40.
- Stark L. A minor injuries clinic: a year of change, innovation and integrated working. Emergency Nurse. 2004; 12(6):14–16 [PubMed: 15516085]
- 41.
- Taylor J. The rise of the walk-in centre. Nursing Times. 2008; 104(33):16–18 [PubMed: 18780703]
- 42.
- Vaughan J. Developing a nurse-led paracentesis service in an ambulatory care unit. Nursing Standard. 2013; 28(4):44–50 [PubMed: 24063486]
- 43.
- Villasenor S, Krouse HJ. Can the use of urgent care clinics improve access to care without undermining continuity in primary care? Journal of the American Association of Nurse Practitioners. 2016; 28(6):335–341 [PubMed: 26485113]
- 44.
- Ward S. Walk-in centres. On the wrong foot? Health Service Journal. 2001; 111(5767):24–27 [PubMed: 11530545]
- 45.
- Weatherburn G, Ward S, Johnston G, Chisholm S. Off-site expert support for nurses undertaking ECGs in primary care. British Journal of Nursing. 2009; 18(9):551–554 [PubMed: 19448582]
- 46.
- Welch L. Ambulatory care: a decade of evolution. Health Estate. 2009; 63(1):50–53 [PubMed: 19192601]
- 47.
- Zimmerman DR. Community-based urgent care in Israel and worldwide. Israel Journal of Health Policy Research. 2013; 2(1):38 [PMC free article: PMC4016482] [PubMed: 24152917]
Appendices
Appendix A. Review protocol
Table 6Review protocol: Minor injury unit, urgent care centre or walk-in centre
| Review question | Minor injury unit, urgent care centre or walk-in centre |
|---|---|
| Guideline condition and its definition | Acute medical emergencies. |
| Objectives | Is a minor injury unit, urgent care centre or walk-in centre clinically and cost effective: 1. as a stand-alone unit 2. when located on the same site as a full emergency department? |
| Review population | Adults and young people (16 years and over) presenting with a suspected or confirmed AME. |
| Adults and young people (16 years and over). | |
| Line of therapy not an inclusion criterion. | |
|
Interventions and comparators: generic/class; specific/drug (All interventions will be compared with each other, unless otherwise stated) |
Presence of minor injury units, urgent care centres or walk in centres; as stand-alone units. Presence of minor injury units, urgent care centres or walk in centres; within a full emergency department. Absence of minor injury units, urgent care centres or walk in centres; absence. |
| Outcomes |
|
| Study design |
Systematic Review RCT Quasi-RCT Non randomised study Prospective cohort study Retrospective cohort study Controlled before and after study Before and after study |
| Unit of randomisation |
Patient. Hospital. Ward. |
| Crossover study | Not permitted. |
| Minimum duration of study | Not defined. |
| Subgroup analyses if there is heterogeneity |
|
| Exclusions | UK only. |
| Search criteria |
Databases: Medline, Embase, the Cochrane Library. Date limits for search: 1995. Language: English only. |
Appendix B. Clinical article selection
Appendix C. Forest plots
C.1. Stand-alone units versus absence
C.2. Co-located on the same site as the ED versus absence
Appendix D. Clinical evidence tables
Download PDF (405K)
Appendix E. Economic evidence tables
Download PDF (418K)
Appendix F. GRADE tables
Table 7Clinical evidence profile: Stand-alone units versus absence
| Quality assessment | No of patients | Effect | Quality | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Stand-alone units | Absence | Relative (95% CI) | Absolute | ||
| ED avoidance (follow-up mean 1 years; measured with: Mean monthly attendance rates; Better indicated by lower values) | ||||||||||||
| 2 | observational studies | no serious risk of bias2 | no serious inconsistency | no serious indirectness | serious1 | None | not applicable | not applicable | not calculable | MD 194.83 lower (322 to 67.66 lower) |
⨁◯◯◯ VERY LOW | IMPORTANT |
| ED avoidance (follow-up mean 1 years; assessed with: Annual attendance rates (per 1000 population)) | ||||||||||||
| 1 | observational studies | no serious risk of bias2 | no serious inconsistency | no serious indirectness | serious1 | None | not applicable | not applicable | 1.17 (1.03 to 1.33) | not calculable |
⨁◯◯◯ VERY LOW | IMPORTANT |
- 1
Downgraded by 1 increment if the confidence interval crossed 1 MID, and downgraded by 2 increments if the confidence interval crossed both MIDs.
- 2
All non-randomised studies automatically downgraded due to selection bias. Studies may be further downgraded by 1 increment if other factors suggest additional high risk of bias, or 2 increments if other factors suggest additional very high risk of bias.
Table 8Clinical evidence profile: Co-located on the same site as the ED versus absence
| Quality assessment | No of patients | Effect | Quality | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Co-located with ED | Absence | Relative (95% CI) | Absolute | ||
| Avoidable adverse events (re-consultations) (follow-up 4 weeks; assessed with: Number of re-consultations - ED patients only) | ||||||||||||
| 1 | observational studies | serious1 | no serious inconsistency | no serious indirectness | no serious imprecision | none |
54/115 (47%) | 48.9% | RR 0.96 (0.77 to 1.2) | 20 fewer per 1000 (from 112 fewer to 98 more) |
⨁◯◯◯ LOW | CRITICAL |
| Avoidable adverse events (re-consultations) (follow-up 4 weeks; assessed with: Number of re-consultations (ED + WiC patients combined)) | ||||||||||||
| 1 | observational studies | serious1 | no serious inconsistency | no serious indirectness | no serious imprecision | none |
149/330 (45.2%) | 48.9% | RR 0.92 (0.79 to 1.08) | 39 fewer per 1000 (from 103 fewer to 39 more) |
⨁◯◯◯ LOW | CRITICAL |
| ED avoidance (follow-up 6 months; measured with: Patient throughput (mean monthly attendances); Better indicated by lower values) | ||||||||||||
| 1 | observational studies | no serious risk of bias3 | no serious inconsistency | no serious indirectness | very serious2 | none | not applicable | not applicable | not calculable | MD 542 higher (347 lower to 1431 higher) |
⨁◯◯◯ VERY LOW | IMPORTANT |
| ED avoidance (follow-up 1 year; measured with: Mean monthly attendances); Better indicated by lower values) | ||||||||||||
| 1 | observational studies | no serious risk of bias3 | no serious inconsistency | no serious indirectness | serious1 | none | not applicable | not applicable | not calculable | MD 349 lower (696 to 2 lower) |
⨁◯◯◯ VERY LOW | IMPORTANT |
| Waiting time in ED (follow-up 3 months; assessed with: Cases complying with A&E 4 hour waiting target) | ||||||||||||
| 1 | observational studies | no serious risk of bias3 | no serious inconsistency | no serious indirectness | no serious imprecision | none |
743/785 (94.6%) | 87.4% | RR 1.08 (1.05 to 1.11) | 70 more per 1000 (from 44 more to 96 more) |
⨁⨁◯◯ LOW | CRITICAL |
| Waiting time in ED (follow-up 3 months; assessed with: Cases complying with A&E 4 hour waiting target) | ||||||||||||
| 1 | observational studies | no serious risk of bias3 | no serious inconsistency | no serious indirectness | no serious imprecision | none |
1466/1546 (94.8%) | 87.4% | RR 1.09 (1.06 to 1.11) | 79 more per 1000 (from 52 more to 96 more) |
⨁⨁◯◯ LOW | CRITICAL |
| Waiting time in ED (follow-up 3 months; assessed with: Cases complying with A&E 4 hour waiting target) | ||||||||||||
| 1 | observational studies | no serious risk of bias3 | no serious inconsistency | no serious indirectness | no serious imprecision | none |
743/785 (94.6%) | 94.8% | RR 1 (0.98 to 1.02) | 0 fewer per 1000 (from 19 fewer to 19 more) |
⨁⨁◯◯ LOW | CRITICAL |
| Waiting time in ED (follow-up 3 years; measured with: Average change in time to clinician (mins) per year; Better indicated by lower values) | ||||||||||||
| 1 | observational studies | no serious risk of bias3 | no serious inconsistency | no serious indirectness | no serious imprecision | none | not applicable | not applicable | not calculable | MD 11 lower (14 to 8 lower) |
⨁⨁◯◯ LOW | CRITICAL |
| Mortality (follow-up 3 years; measured with: Number dying per 1000 attendees; Better indicated by lower values) | ||||||||||||
| 1 | observational studies | no serious risk of bia3s | no serious inconsistency | no serious indirectness | unable to assess imprecision without MID values | none | not applicable | not applicable | not calculable | MD 1.8 higher (1.6 to 2 higher) | - | IMPORTANT |
- 1
Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias.
- 2
Downgraded by 1 increment if the confidence interval crossed 1 MID or by 2 increments if the confidence interval crossed both MIDs.
- 3
All non-randomised studies automatically downgraded due to selection bias. Studies may be further downgraded by 1 increment if other factors suggest additional high risk of bias, or 2 increments if other factors suggest additional very high risk of bias.
Appendix G. Excluded clinical studies
Table 9Studies excluded from the clinical review
| Study | Exclusion reason |
|---|---|
| Banerjee 20122 | Inappropriate comparison (audit – no comparator) |
| Beales 19953 | Inappropriate comparison (descriptive article – no comparator) |
| Bickerton 20055 | Inappropriate comparison. Incorrect interventions (retrospective case note analysis – no intervention or comparator) |
| Bickerton 20124 | No relevant outcomes reported |
| Byrne 20006 | Not review population (exclusively minor injuries patients) |
| CASPERS 20167 | Non-UK study (USA). Full text next available |
| Castledine 20088 | Inappropriate comparison. Incorrect interventions (descriptive article – no intervention or comparator) |
| Chalder 20079 | No extractable data |
| Chapman 200411 | Systematic review is not relevant to review question or unclear PICO |
| Dale 199612 | Inappropriate comparison (no comparator) |
| Davis 200513 | Inappropriate comparison (descriptive article – no comparator) |
| Desborough 201214 | Systematic review is not relevant to review question or unclear PICO |
| Freij 199616 | No relevant outcomes reported |
| Gnani 201317 | Inappropriate comparison (descriptive article – no comparator) |
| Grant 200218 | Incorrect comparison (walk-in centre versus GP practice) |
| Gray 200319 | Inappropriate comparison (descriptive study - no comparator) |
| Heaney 199720 | No extractable outcome data |
| Ismail 201322 | Systematic review is not relevant to review question or unclear PICO |
| Jackson 200523 | Inappropriate comparison. No relevant outcomes (descriptive qualitative article – no comparator) |
| Land 201324 | Inappropriate comparison. No relevant outcomes (patient survey – no comparator) |
| Marshall 199825 | Inappropriate comparison (descriptive article – no comparator) |
| Mcintosh 199626 | Inappropriate comparison (descriptive non-UK article – no comparator) |
| Paxton 199728 | Incorrect interventions. Inappropriate comparison (patient survey – no comparator) |
| Roberts 199829 | Systematic review is not relevant to review question or unclear PICO |
| Rourke 200930 | Not review population (exclusively ENT conditions) |
| Rudge 201331 | Inappropriate comparison (distance to MIU) |
| Sakr 200332 | Not review population (exclusively minor injuries patients) |
| Salisbury 200236 | Incorrect comparison (walk-in centre versus GP practice) |
| Salisbury 200234 | Inappropriate comparison (descriptive article – no comparator) |
| Salisbury 200333 | No extractable outcome data |
| Salisbury 200337 | Systematic review is not relevant to review question or unclear PICO |
| Simpson 200138 | Unclear intervention (centralisation of 3 A&E departments involving several changes including a new MIU and EAU) |
| Snooks 200439 | Not review population (exclusively minor injuries patients) |
| Stark 200440 | Inappropriate comparison (descriptive article – no comparator) |
| Taylor 200841 | Inappropriate comparison (descriptive article – no comparator) |
| Vaughan 201342 | Incorrect interventions (nurse-led versus doctor-led hospital service) |
| VILLASENOR 201643 | Systematic review. No relevant references |
| Ward 200144 | Inappropriate comparison (no comparator) |
| Weatherburn 200945 | Not review intervention (telemetric cardiology service) |
| Welch 200946 | Inappropriate comparison (descriptive article – no comparator) |
| Zimmerman 201347 | Systematic review is not relevant to review question or unclear PICO |
Appendix H. Excluded health economic studies
No studies were excluded.
- Minor injury unit, urgent care centre or walk-in centre - Emergency and acute me...Minor injury unit, urgent care centre or walk-in centre - Emergency and acute medical care in over 16s: service delivery and organisation
Your browsing activity is empty.
Activity recording is turned off.
See more...










