Copyright Notice
Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Bookshelf ID: NBK564287PMID: 33226750
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 140-65-8
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of pramoxine during breastfeeding. Direct ingestion of pramoxine has resulted mostly of nausea and vomiting, with no serious toxicity;[1] however, it should be wiped off thoroughly prior to nursing if it is being applied to the breast or nipple area.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Spiller HA, Baker SD, Smith GW, et al. Evaluation of pramoxine ingestion as reported to poison centers. Ann Pharmacother 2006;40:996-7. [PubMed: 16595565]
Substance Identification
Substance Name
Pramoxine
CAS Registry Number
637-58-1
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients.[J Dermatolog Treat. 2009]A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients.Young TA, Patel TS, Camacho F, Clark A, Freedman BI, Kaur M, Fountain J, Williams LL, Yosipovitch G, Fleischer AB Jr. J Dermatolog Treat. 2009; 20(2):76-81.
- The fetal safety of hydrocortisone-pramoxine (Proctofoam-HC) for the treatment of hemorrhoids in late pregnancy.[J Obstet Gynaecol Can. 2011]The fetal safety of hydrocortisone-pramoxine (Proctofoam-HC) for the treatment of hemorrhoids in late pregnancy.Ebrahimi N, Vohra S, Gedeon C, Akoury H, Bernstein P, Pairaudeau N, Cormier J, Dontigny L, Arsenault MY, Fortin C, et al. J Obstet Gynaecol Can. 2011 Feb; 33(2):153-158.
- IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.[Proc Natl Acad Sci U S A. 2016]IL-33/ST2 signaling excites sensory neurons and mediates itch response in a mouse model of poison ivy contact allergy.Liu B, Tai Y, Achanta S, Kaelberer MM, Caceres AI, Shao X, Fang J, Jordt SE. Proc Natl Acad Sci U S A. 2016 Nov 22; 113(47):E7572-E7579. Epub 2016 Nov 7.
- Review Allergic Contact Dermatitis to Pramoxine (Pramocaine).[Dermatitis. 2021]Review Allergic Contact Dermatitis to Pramoxine (Pramocaine).Kimyon RS, Schlarbaum JP, Liou YL, Hylwa SA, Warshaw EM. Dermatitis. 2021 Jan-Feb 01; 32(1):32-37.
- Local cooling for relieving pain from perineal trauma sustained during childbirth.[Cochrane Database Syst Rev. 2007]Local cooling for relieving pain from perineal trauma sustained during childbirth.East CE, Begg L, Henshall NE, Marchant P, Wallace K. Cochrane Database Syst Rev. 2007 Oct 17; (4):CD006304. Epub 2007 Oct 17.
- Pramoxine - Drugs and Lactation Database (LactMed®)Pramoxine - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...