Figure three is a line and square drawing depicting the analytic framework for colorectal cancer. The two cell lines, either animal or human, are exposed to alcohol. Other risk  factors, along with alcohol metabolites, induce cancer, or its promotion or progression, to colorectal cancer.

Figure 3Analytical framework for colorectal cancer

KQ: Key Question

KQ 3: effect of alcohol on stages of carcinogenesis

KQ 4: effect of alcohol and other risk factors on stages of carcinogenesis

From: 2, Methods

Cover of Alcohol Consumption and Cancer Risk
Alcohol Consumption and Cancer Risk: Understanding Possible Causal Mechanisms for Breast and Colorectal Cancers.
Evidence Reports/Technology Assessments, No. 197.
Oyesanmi O, Snyder D, Sullivan N, et al.

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