Table 10Overall results from animal colorectal cancer studies

Study* Confounding ExposureCancer FormationSurrogate Outcome MeasureAuthors Reported on Causal MechanismNumber of Links in the Pathway of Carcinogenesis
Hayashi et al. 2007118YNYY1
Perez-Holanda et al. 200573YNNN0
Pronko et al. 2002120NNYY1
Roy et al. 2002121NNYN1
Homann et al. 200070NNYN1
Choi et al. 1999124NNYY1
Hakkak et al. 1996119NNYY1
Simanowski et al. 1994125NNYY1
Niwa et al. 1991126YNYY1
Seitz et al. 1990122YNYY1
McGarrity et al. 1988129YNYY1
Hamilton et al. 1988130YNYY1
Garzon et al. 1987128YYNY1
Hamilton et al. 1987132YNYY1
Hamilton et al. 1987131YNYY1
Simanowski et al. 1986127NNYY1
Nelson et al. 1985116YNNN0
Seitz et al. 1985123YNYY1
Howarth et al. 1984117YNNN0

Confounding exposure: did study administer a carcinogen and/or acetaldehyde?

Y: there was confounding exposure

N: there was no confounding exposure

From: 4, Discussion

Cover of Alcohol Consumption and Cancer Risk
Alcohol Consumption and Cancer Risk: Understanding Possible Causal Mechanisms for Breast and Colorectal Cancers.
Evidence Reports/Technology Assessments, No. 197.
Oyesanmi O, Snyder D, Sullivan N, et al.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.