Data elementComments, coding for data extraction
Ref id
First author, year
Total number included in the study
Dropouts and withdrawals or untested
Activity assay: number of patients with non-interpretable test results
Genotyping: number of patients with non-interpretable test results
SNPs testedSpecify SNPs
First comparison
GenotypesHeterozygous or homozygous for variant(s)/wild type
Normal or hyperactivity (or controls)Numbers of participants with particular enzyme activity, with genotype
Intermediate or low/absent activity (or cases)Numbers of participants with particular enzyme activity, with genotype
Second comparison
GenotypeHomozygous for variant(s)/Wild type or heterozygous for variants
Normal/hyperactivity/intermediate activity (or controls)Numbers of participants with particular enzyme activity, with genotype
Low/absent activity (or cases)Numbers of participants with particular enzyme activity, with genotype
Number of allele specific subgroups

Abbreviations: Ref id = unique reference identification number; TPMT = thiopurine methyltransferase

From: Appendix B, Data extraction and related forms

Cover of Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs
Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs.
Evidence Reports/Technology Assessments, No. 196.
Booth RA, Ansari MT, Tricco AC, et al.

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