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Cover of Prudent Practices in the Laboratory

Prudent Practices in the Laboratory

Handling and Management of Chemical Hazards

Updated Version


Washington (DC): National Academies Press (US); .


This edition of Prudent Practices in the Laboratory builds on the work provided in previous editions. Among other changes, it has two new chapters, one on Emergency Planning and one on Laboratory Security, described above, and the discussion of EHS (environment, health, and safety) management systems has been extensively revised. Chapters 2, 3, and 10 cover administrative and organizational concerns that affect the laboratory environment; Chapters 4–8 discuss practical concerns when working in a laboratory; Chapter 9 discusses laboratory facilities; and Chapter 11 provides an overview of federal regulations that affect laboratory activities. Acknowledging the stronger regulatory environment that exists today, this edition provides more references to relevant codes, standards, and regulations than the prior versions. This is not intended to imply that safety has become a matter of regulation rather than of good practice; it is a reflection of laboratory practice today and is intended to provide a resource for personnel who must remain in compliance with these regulations or face legal consequences.


This study was supported by the U.S. Department of Energy under grant number DE-FG02-08ER15932; the National Institutes of Health under contract number N01-OD-4-2139, TO #200; and the National Science Foundation under grant number CHE-0740356. Additional support was received from Air Products and Chemicals, Inc.; the American Chemical Society; E. I. du Pont de Nemours and Company; Eastman Chemical Company; the Howard Hughes Medical Institute; and PPG Industries.

Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of the organizations or agencies that provided support for the project.

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

Copyright © 2011, National Academy of Sciences.
Bookshelf ID: NBK55878PMID: 21796825DOI: 10.17226/12654


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