Structured Abstract

Contents

• Preface
• Acknowledgments
• Key Informants
• Technical Expert Panel
• Peer Reviewers
• Evidence Summary
  • Main Points
  • Background and Purpose
  • Methods
  • Results
  • Limitations
  • Implications and Conclusions
• Introduction
  • Background and Objectives
  • Key Questions
• Methods
  • Searching for the Evidence
  • Study Eligibility
  • Screening Studies for Eligibility
  • Data Extraction
  • Intervention Coding
  • Assessment of Risk of Bias
  • Data Synthesis
  • Grading the Strength of Evidence for Major Comparisons and Outcomes
  • Assessing Applicability
• Results
  • Qualitative Categorization
  • Brief Behavioral Interventions
  • Nonbrief Behavioral Interventions
  • Systematic Reviews of Treatments for Alcohol Use in the College Setting
  • Pharmaceutical Interventions
  • Comorbid Psychiatric Disorders in Adolescents With SUD
• Discussion
  • Key Findings
  • Findings in Relationship to What Is Already Known
  • Applicability
  • Implications for Clinical and Policy Decision Making
  • Limitations of the Systematic Review Process
  • Limitations of the Evidence Base
  • Recommendations for Future Research
  • Conclusions
• References
• Abbreviations and Acronyms
• Appendixes
  • Appendix A. Search Strategies
  • Appendix B. Excluded Studies
  • Appendix C. Intervention Coding Manual
  • Appendix D. Baselines
  • Appendix E. Outcomes Extracted by Study
  • Appendix F. Brief interventions: Detailed Results
  • Appendix G. Nonbrief Interventions: Detailed Results
  • Appendix H. Risk of Bias Assessments
  • Appendix I. Technical Appendix
    TA Trikalinos and DW Steele.

Suggested citation:

Steele DW, Becker SJ, Danko KJ, Balk EM, Saldanha IJ, Adam GP, Bagley SM, Friedman C, Spirito A, Scott K, Ntzani EE, Saeed I, Smith B, Popp J, Trikalinos TA. Interventions for Substance Use Disorders in Adolescents: A Systematic Review. Comparative Effectiveness Review No. 225. (Prepared by the Brown Evidence-based Practice Center under Contract No. 290-2015-00002-I.) AHRQ Publication No. 20-EHC014. Rockville, MD: Agency for Healthcare Research and Quality. May 2020. Posted final reports are located on the Effective Health Care Program search page. DOI: https://doi.org/10.23970/AHRQEPCCER225.

This report is based on research conducted by the Brown Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2015-00002-I). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

None of the investigators have any affiliations or financial involvement that conflicts with the material presented in this report.

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