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Cover of Alzheimer’s Disease

Alzheimer’s Disease

Editor: Thomas Wisniewski, MD.

Editor Information
Brisbane (AU): Codon Publications; .
ISBN-13: 978-0-6468096-8-7

Alzheimer’s disease (AD) is the most common cause of dementia. No effective pharmaceutical agents exist to halt or slow down the disease progression. There is a tremendous imperative to gain a better understanding of the pathogenesis of AD and to develop effective treatments. This book brings together an international team of experts to provide a comprehensive and up-to-date overview of AD. The most current information on several critical aspects of AD are presented, providing the readers with a broad picture of the underlying neuropathology, genetics, proteomics, risk factors, novel biomarkers, and potential interventions. Chapters 1–5 discuss the underlying AD pathogenesis using genomic and proteomic approaches, linking diverse pathways that can lead to complex metabolic dysfunction. Chapter 6 reviews the potential role of trace metals in AD, while Chapter 7 examines the diversity of Aβ species involved in AD pathology. Chapter 8 discusses the contributions of white matter degeneration in AD. Chapter 9 examines the potential intriguing role of the brain-gut-microbiota axis in mediating AD. Chapters 10 and 11 discuss potential biomarkers for AD, such as deficits in ocular exploration and early language impairments, respectively. Chapters 12–15 examine possible novel preventative and/or therapeutic methodologies such as exercise, optimizing depression therapy, and diverse psychosocial interventions. The book will be of value to clinicians and health professionals caring for patients with AD, and will provide a comprehensive and thought-provoking introduction to young investigators interested in translational aspects of the AD and related dementias.

Contents

Alzheimer’s Disease

ISBN: 978-0-6468096-8-7

DOI: http://dx.doi.org/10.15586/alzheimersdisease.2019

Edited by

Thomas Wisniewski, MD, New York University Alzheimer’s Disease Center, New York University School of Medicine, New York, USA

Published by

Codon Publications

Brisbane, Australia

Copyright© 2019 Codon Publications

Copyright of individual chapters belongs to the respective authors. The authors grant unrestricted publishing and distribution rights to the publisher. The electronic versions of the chapters are published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). https://creativecommons.org/licenses/by-nc/4.0/. Users are allowed to share and adapt the chapters for any non-commercial purposes as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source. The book in its entirety is subject to copyright by the publisher. The reproduction, modification, republication and display of the book in its entirety, in any form, by anyone, for commercial purposes are strictly prohibited without the written consent of the publisher.

Notice to the user

The views and opinions expressed in this book are believed to be accurate at the time of publication. The publisher, editors or authors cannot be held responsible or liable for any errors, omissions or consequences arising from the use of the information contained in this book. The publisher makes no warranty, implicit or explicit, with respect to the contents of this book, or its use.

First Published in November 2019

Printed in Australia

Copyright © 2019 Codon Publications.

Copyright of individual chapters belongs to the respective authors. The authors grant unrestricted publishing and distribution rights to the publisher. The electronic versions of the chapters are published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Users are allowed to share and adapt the chapters for any non-commercial purposes as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source. The book in its entirety is subject to copyright by the publisher. The reproduction, modification, republication and display of the book in its entirety, in any form, by anyone, for commercial purposes are strictly prohibited without the written consent of the publisher.

Bookshelf ID: NBK552148PMID: 31895508DOI: 10.15586/alzheimersdisease.2019

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