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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].
Show details| Time After Starting | Time After Stopping | ALT (U/L) | Alk P (U/L) | Bilirubin* (mg/dL) | Other |
|---|---|---|---|---|---|
| 0 | Tizanidine started | ||||
| 2 days | 0 | Normal | Normal | Normal | |
| 16 days | 0 | Tizanidine stopped | |||
| 18 days | 2 days | 830 | 187 | 26.5 | Admission. INR=1.6 |
| 22 days | 8 days | 270 | 36.0 | ||
| 24 days | 10 days | 60 | 30.0 | ||
| 26 days | 12 days | 30 | 4.0 | ||
| 30 days | 16 days | 14 | 1.0 | Single dose of tizanidine | |
| 31 (1)** days | 17 (1) days | 155 | 1.0 | ||
| 32 (2) days | 18 (2) days | 30 | 1.0 | ||
| Normal Values | <30 | <100 | <1.2 | ||
- A Case of Tizanidine Withdrawal Syndrome: Features and Management in the Emergency Department.[Cureus. 2023]A Case of Tizanidine Withdrawal Syndrome: Features and Management in the Emergency Department.Morgom M, Sabir DM, Elbashir H, Saeed L, Alamin A, Abuazab Y, Abdelrahman N. Cureus. 2023 Nov; 15(11):e49248. Epub 2023 Nov 22.
- Involvement of imidazoline receptors in the centrally acting muscle-relaxant effects of tizanidine.[Eur J Pharmacol. 2002]Involvement of imidazoline receptors in the centrally acting muscle-relaxant effects of tizanidine.Honda M, Sekiguchi Y, Sato N, Ono H. Eur J Pharmacol. 2002 Jun 12; 445(3):187-93.
- A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.[Curr Med Res Opin. 1981]A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.Smolenski C, Muff S, Smolenski-Kautz S. Curr Med Res Opin. 1981; 7(6):374-83.
- Review Chlorzoxazone.[LiverTox: Clinical and Researc...]Review Chlorzoxazone.. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. 2012
- Review Tizanidine: neuropharmacology and mechanism of action.[Neurology. 1994]Review Tizanidine: neuropharmacology and mechanism of action.Coward DM. Neurology. 1994 Nov; 44(11 Suppl 9):S6-10; discussion S10-1.
- [Table, Laboratory Values]. - LiverTox[Table, Laboratory Values]. - LiverTox
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