Figure 7.1. Molecular structure of ROCKs.

Figure 7.1

Molecular structure of ROCKs. ROCK amino acid sequence comprises a kinase domain located at the amino terminus, a coiled-coil region containing the Rho-binding domain (Rho BD), and a pleckstrin-homology domain (PHD) with a cysteine-rich domain (CRD). ROCK-1 and ROCK-2 are highly homologous with an overall amino acid sequence identity of 65%.

From: Chapter 7, Rho Kinase in Vascular Smooth Muscle

Cover of Regulation of Vascular Smooth Muscle Function
Regulation of Vascular Smooth Muscle Function.
Khalil RA.
San Rafael (CA): Morgan & Claypool Life Sciences; 2010.
Copyright © 2010 by Morgan & Claypool Life Sciences.

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