Table 6.1

Subcellular Distribution of PKC

EnzymeMolecular weight (kDa)Cell typeResting stateActivated stateReference
PKCFerret portal veinCytosolic PerinuclearSurface membrane Perinuclear[134]
Cultured rat aortic smooth muscle cellsCytosolic fractionMembrane fraction[135]
α-PKC74–82Bovine aortaCytosolic fractionMembrane fraction[136]
Ferret portal veinCytosolic fractionSurface membrane[137]
Cultured rat aorta cellsCytosolic fractionNuclear fraction[138]
Carotid arteryCytosolic fractionParticulate fraction[139]
Rat mesenteric arteryCytosolic/Membrane[140]
β-PKC80–82Cultured rat aorta cellsCytosolic fractionNuclear fraction[138]
Carotid arteryCytosolic fractionParticulate fraction[139]
γ-PKC70–82Rat mesenteric arteryCytosolic fractionCytosolic fraction[140]
δ-PKC76–82Rat aortaCytoskeleton OrganellesCytoskeleton Organelles[141]
Rat mesenteric arteryMembrane fraction[140]
ϵ-PKC90–97Ferret aortaCytosolSurface membrane[142]
Rat mesenteric arteryCytosolic/Membrane[140]
ζ-PKC64–82Ferret aorta and portal veinPerinuclearIntranuclear[142]
Rat aortaPerinuclearIntranuclear[141]
Rat mesenteric arteryCytosolic fraction[140]

From: Chapter 6, Protein Kinase C

Cover of Regulation of Vascular Smooth Muscle Function
Regulation of Vascular Smooth Muscle Function.
Khalil RA.
San Rafael (CA): Morgan & Claypool Life Sciences; 2010.
Copyright © 2010 by Morgan & Claypool Life Sciences.

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