Table 1Example evidence profile table

Quality assessmentSummary of findings
No. of patientsEffect
No. of studiesQuality of included studiesConsistencyDirectnessOther modifying factorsCBTWaitlistEffect sizeLikelihood of clinically important effectOverall qualityImportance
Carbamazepine versus placebo
Mania: change score at endpoint (manic only)
Weisler 2004
Weisler 2005
Sign: 1+ (−1)NoneAcute maniaStrong effect (+1)134146WMD = −6.87 (−9.24, −4.49)Very likely (favouring carbamazepine)ModerateCritical
Leaving treatment early for any reason
Weisler 2004
Weisler 2005
Sign: 1+ (−1)Significant heterogeneity (−1): random effects model usedAcute maniaNone134146RR (random effects) = 0.79 (0.59, 1.06)Likely (favouring carbamazepine)LowCritical


Cover of Antenatal and Postnatal Mental Health
Antenatal and Postnatal Mental Health: The NICE Guideline on Clinical Management and Service Guidance.
NICE Clinical Guidelines, No. 45.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2007.
Copyright © 2007, The British Psychological Society & The Royal College of Psychiatrists.

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