Table 49Summary evidence profile for studies of light therapy and oestrogen in the treatment of depression in the postnatal period

Light therapyOestrogen
Study IDsEPPERSON2004GREGOIRE1996
Overall quality of evidenceLowModerate
Depression above threshold at endpointRR = 1 (0.36, 2.75) (K = 1; n = 10)
RMptreat 01.01
RR = 0.47 (0.3, 0.74) (K = 1; n = 64)
RMptreat 02.03
Depression symptoms at endpointN/AWMD = − 5.75 (−8.66, −2.84) (K = 1; n = 45)
RMptreat 02.02
Anxiety symptoms at endpointN/AN/A
% attrition rate, treatment group versus standard care0% versus 40% (K = 1; n = 10)
RMptreat 01.02
22% versus 39% (K = 1; n = 64)
RMptreat 02.00
% attrition rate due to side effects, treatment group versus standard careN/AN/A
% side effects treatment group versus standard careN/AN/A

Notes: RR = relative risk (95% CI); K = number of trials contributing to the summary statistic; n = number of participants; N/A = not available; ‘RMptreat nn.nn’ and ‘RMpprev nn.nn’ refer to the relevant forest plot in Appendix 20

From: 7, THE PHARMACOLOGICAL TREATMENT OF MENTAL DISORDERS IN PREGNANT AND BREASTFEEDING WOMEN

Cover of Antenatal and Postnatal Mental Health
Antenatal and Postnatal Mental Health: The NICE Guideline on Clinical Management and Service Guidance.
NICE Clinical Guidelines, No. 45.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2007.
Copyright © 2007, The British Psychological Society & The Royal College of Psychiatrists.

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