Table 11Summary evidence profile for psychological treatments versus standard care for the prevention of depression: by treatment

DebriefingStructured psychological treatments (CBT/IPT)Social support (individual or group)Multi-modalPsycho-education (booklet or group)
Study IDsSMALL2000
RYDING2004
GAMBLE2005
GORMANunpublished
ZLOTNICK2001
HAGAN2004
ZLOTNICK2006
DENNIS2003
STAMP1995
ARMSTRONG 1999
MEYER1994
BRUGHA2000
WEBSTER2003
Overall quality of evidenceModerateModerateModerateModerateModerate
Depression above threshold at endpoint or first available measureRR = 1.09 (0.85, 1.41) (K = 3; n = 1,166)
RMnppr 01.02
RR = 0.52 (0.3, 0.9) (K = 4; n = 336)
RMnppr 01.02
RR (random effects) = 0.51 (0.26, 0.98) (K = 2; n = 169)
RMnppr 01.03
RR = 0.36 (0.15, 0.87) (K = 2; n = 165)
RMnppr 01.02
RR = 0.85 (0.63, 1.15) (K = 2; n = 559)
RMnppr 01.02
% attrition rate, treatment group versus standard care9% versus 12% (K = 3; n = 1,306)
RMnppr 02.02
11% versus 4% (K = 4; n = 380)
RMnppr 02.02
8% versus 5% (K = 2; n = 186)
RMnppr 02.02
20% versus 20% (K = 1; n = 215)
RMnppr 02.02
29% versus 32% (K = 2; n = 809)
RMnppr 02.02

Notes: RR = relative risk (95% CI); K = number of trials contributing to the summary statistic; n = number of participants; ‘RMnppr nn.nn’ refers to the relevant forest plot in Appendix 20

From: 6, PSYCHOLOGICAL AND PSYCHOSOCIAL INTERVENTIONS

Cover of Antenatal and Postnatal Mental Health
Antenatal and Postnatal Mental Health: The NICE Guideline on Clinical Management and Service Guidance.
NICE Clinical Guidelines, No. 45.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2007.
Copyright © 2007, The British Psychological Society & The Royal College of Psychiatrists.

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