FIGURE 12. Deglutitive inhibition and esophageal muscle refractoriness recorded by high-resolution manometry.

FIGURE 12

Deglutitive inhibition and esophageal muscle refractoriness recorded by high-resolution manometry. (A) Normal swallow-induced peristalsis and LES relaxation. (B) If the second swallow follows too soon after the first one, contraction amplitude of the second one is smaller than the first one, which is due to the esophageal muscle refractory period. (C) Multiple swallows at close intervals—note that only last swallow elicits peristaltic contraction of the esophagus. Each swallow following the first one inhibits the one preceding it, the so-called deglutitive inhibition.

From: Recording Techniques

Cover of Motor Function of the Pharynx, Esophagus, and its Sphincters
Motor Function of the Pharynx, Esophagus, and its Sphincters.
Mittal RK.
San Rafael (CA): Morgan & Claypool Life Sciences; 2011.
Copyright © 2011 by Morgan & Claypool Life Sciences.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.